diff --git a/tests/test_capture.py b/tests/test_capture.py
index ba37be8..8f70c9e 100644
--- a/tests/test_capture.py
+++ b/tests/test_capture.py
@@ -87,7 +87,7 @@ def test_show_capture_with_build(tmp_path, show_capture):
     """
     tmp_path.joinpath("workflow.py").write_text(textwrap.dedent(source))
 
-    result = run_in_subprocess(("uv", "run", "python", "workflow.py"), cwd=tmp_path)
+    result = run_in_subprocess(("python", "workflow.py"), cwd=tmp_path)
 
     assert result.exit_code == ExitCode.FAILED
 
@@ -128,7 +128,7 @@ def test_wrong_capture_method(tmp_path):
     """
     tmp_path.joinpath("workflow.py").write_text(textwrap.dedent(source))
 
-    result = run_in_subprocess(("uv", "run", "python", "workflow.py"), cwd=tmp_path)
+    result = run_in_subprocess(("python", "workflow.py"), cwd=tmp_path)
     assert result.exit_code == ExitCode.CONFIGURATION_FAILED
     assert "Value 'a' is not a valid" in result.stdout
     assert "Traceback" not in result.stdout
@@ -255,7 +255,7 @@ def test_capturing_unicode_with_build(tmp_path, method):
     tmp_path.joinpath("workflow.py").write_text(
         textwrap.dedent(source), encoding="utf-8"
     )
-    result = run_in_subprocess(("uv", "run", "python", "workflow.py"), cwd=tmp_path)
+    result = run_in_subprocess(("python", "workflow.py"), cwd=tmp_path)
     assert result.exit_code == ExitCode.OK
     assert "1  Succeeded" in result.stdout
 
diff --git a/tests/test_config.py b/tests/test_config.py
index c46f5ed..eaa0934 100644
--- a/tests/test_config.py
+++ b/tests/test_config.py
@@ -114,7 +114,7 @@ def test_paths_are_relative_to_configuration_file(tmp_path):
     session = build(paths=[Path("src")])
     """
     tmp_path.joinpath("script.py").write_text(textwrap.dedent(source))
-    result = run_in_subprocess(("uv", "run", "python", "script.py"), cwd=tmp_path)
+    result = run_in_subprocess(("python", "script.py"), cwd=tmp_path)
     assert result.exit_code == ExitCode.OK
     assert "1  Succeeded" in result.stdout
 
diff --git a/tests/test_dag_command.py b/tests/test_dag_command.py
index 3ca41ba..7c0c4fc 100644
--- a/tests/test_dag_command.py
+++ b/tests/test_dag_command.py
@@ -92,7 +92,7 @@ def test_create_graph_via_task(tmp_path, format_, layout, rankdir):
     tmp_path.joinpath("input.txt").touch()
 
     result = subprocess.run(
-        ("uv", "run", "python", "task_example.py"),
+        ("python", "task_example.py"),
         cwd=tmp_path,
         check=True,
         capture_output=True,
diff --git a/tests/test_execute.py b/tests/test_execute.py
index 1a23316..6532b48 100644
--- a/tests/test_execute.py
+++ b/tests/test_execute.py
@@ -26,7 +26,7 @@ from tests.conftest import run_in_subprocess
 def test_python_m_pytask(tmp_path):
     tmp_path.joinpath("task_module.py").write_text("def task_example(): pass")
     result = run_in_subprocess(
-        ("uv", "run", "python", "-m", "pytask", tmp_path.as_posix())
+        ("python", "-m", "pytask", tmp_path.as_posix())
     )
     assert result.exit_code == ExitCode.OK
 
@@ -602,7 +602,7 @@ def test_execute_tasks_via_functional_api(tmp_path):
     """
     tmp_path.joinpath("task_module.py").write_text(textwrap.dedent(source))
     result = subprocess.run(
-        ("uv", "run", "python", tmp_path.joinpath("task_module.py").as_posix()),
+        ("python", tmp_path.joinpath("task_module.py").as_posix()),
         check=False,
     )
     assert result.returncode == ExitCode.OK
@@ -632,7 +632,7 @@ def test_execute_tasks_multiple_times_via_api(tmp_path):
     """
     tmp_path.joinpath("task_module.py").write_text(textwrap.dedent(source))
     result = run_in_subprocess(
-        ("uv", "run", "python", tmp_path.joinpath("task_module.py").as_posix())
+        ("python", tmp_path.joinpath("task_module.py").as_posix())
     )
     assert result.exit_code == ExitCode.OK
 
diff --git a/tests/test_hook_module.py b/tests/test_hook_module.py
index eba4868..e26288a 100644
--- a/tests/test_hook_module.py
+++ b/tests/test_hook_module.py
@@ -25,8 +25,6 @@ def test_add_new_hook_via_cli(tmp_path, module_name):
 
     if module_name:
         args = (
-            "uv",
-            "run",
             "python",
             "-m",
             "pytask",
@@ -37,8 +35,6 @@ def test_add_new_hook_via_cli(tmp_path, module_name):
         )
     else:
         args = (
-            "uv",
-            "run",
             "pytask",
             "build",
             "--hook-module",
@@ -70,9 +66,6 @@ def test_add_new_hook_via_config(tmp_path, module_name):
 
     if module_name:
         args = (
-            "uv",
-            "run",
-            "--no-project",
             "python",
             "-m",
             "pytask",
@@ -80,7 +73,7 @@ def test_add_new_hook_via_config(tmp_path, module_name):
             "--help",
         )
     else:
-        args = ("uv", "run", "--no-project", "pytask", "build", "--help")
+        args = ("pytask", "build", "--help")
 
     result = run_in_subprocess(args, cwd=tmp_path)
     assert result.exit_code == ExitCode.OK
diff --git a/tests/test_task.py b/tests/test_task.py
index a2f70ad..510619e 100644
--- a/tests/test_task.py
+++ b/tests/test_task.py
@@ -667,7 +667,7 @@ def test_task_will_be_executed_after_another_one_with_function_session(
     tmp_path.joinpath("task_example.py").write_text(textwrap.dedent(source))
 
     result = subprocess.run(
-        ("uv", "run", "python", "task_example.py"),
+        ("python", "task_example.py"),
         cwd=tmp_path,
         capture_output=True,
         check=False,
diff --git a/tests/test_warnings.py b/tests/test_warnings.py
index 8811018..5aae724 100644
--- a/tests/test_warnings.py
+++ b/tests/test_warnings.py
@@ -148,7 +148,7 @@ def test_deprecation_warnings_are_not_captured(tmp_path, warning):
     path_to_warn_module.write_text(textwrap.dedent(warn_module))
 
     # Cannot use runner since then warnings are not ignored by default.
-    result = run_in_subprocess(("uv", "run", "pytask"), cwd=tmp_path)
+    result = run_in_subprocess(("pytask"), cwd=tmp_path)
     assert result.exit_code == ExitCode.OK
     assert "Warnings" not in result.stdout
     assert "warning!!!" not in result.stdout