diff --git a/pkgs/development/python-modules/mlflow-skinny/default.nix b/pkgs/development/python-modules/mlflow-skinny/default.nix
new file mode 100644
index 000000000000..7683c7c045fb
--- /dev/null
+++ b/pkgs/development/python-modules/mlflow-skinny/default.nix
@@ -0,0 +1,73 @@
+{
+  buildPythonPackage,
+  mlflow,
+
+  # build-system
+  setuptools,
+
+  # dependencies
+  cachetools,
+  click,
+  cloudpickle,
+  databricks-sdk,
+  fastapi,
+  gitpython,
+  importlib-metadata,
+  opentelemetry-api,
+  opentelemetry-proto,
+  opentelemetry-sdk,
+  packaging,
+  protobuf,
+  pydantic,
+  python-dotenv,
+  pyyaml,
+  requests,
+  sqlparse,
+  starlette,
+  typing-extensions,
+  uvicorn,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "mlflow-skinny";
+  inherit (mlflow) version src;
+  pyproject = true;
+  __structuredAttrs = true;
+
+  sourceRoot = "${finalAttrs.src.name}/libs/skinny";
+
+  build-system = [ setuptools ];
+
+  dependencies = [
+    cachetools
+    click
+    cloudpickle
+    databricks-sdk
+    fastapi
+    gitpython
+    importlib-metadata
+    opentelemetry-api
+    opentelemetry-proto
+    opentelemetry-sdk
+    packaging
+    protobuf
+    pydantic
+    python-dotenv
+    pyyaml
+    requests
+    sqlparse
+    starlette
+    typing-extensions
+    uvicorn
+  ];
+
+  pythonImportsCheck = [ "mlflow" ];
+
+  # No tests in the skinny subtree.
+  doCheck = false;
+
+  meta = mlflow.meta // {
+    description = "Lightweight version of MLflow that is designed to minimize package size";
+    homepage = "https://github.com/mlflow/mlflow/tree/master/libs/skinny";
+  };
+})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 75a1ff10b2df..33d11b09ed92 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10165,6 +10165,8 @@ self: super: with self; {
 
   mlflow = callPackage ../development/python-modules/mlflow { };
 
+  mlflow-skinny = callPackage ../development/python-modules/mlflow-skinny { };
+
   mlrose = callPackage ../development/python-modules/mlrose { };
 
   mlt = toPythonModule (