diff --git a/pkgs/development/python2-modules/pygobject/default.nix b/pkgs/development/python2-modules/pygobject/default.nix
deleted file mode 100644
index 88a4375b0029..000000000000
--- a/pkgs/development/python2-modules/pygobject/default.nix
+++ /dev/null
@@ -1,62 +0,0 @@
-{
-  lib,
-  stdenv,
-  fetchurl,
-  fetchpatch,
-  python,
-  buildPythonPackage,
-  pkg-config,
-  glib,
-  isPy3k,
-  pythonAtLeast,
-}:
-
-buildPythonPackage rec {
-  pname = "pygobject";
-  version = "2.28.7";
-  format = "other";
-  disabled = pythonAtLeast "3.9";
-
-  src = fetchurl {
-    url = "mirror://gnome/sources/pygobject/${lib.versions.majorMinor version}/${pname}-${version}.tar.xz";
-    sha256 = "0nkam61rsn7y3wik3vw46wk5q2cjfh2iph57hl9m39rc8jijb7dv";
-  };
-
-  outputs = [
-    "out"
-    "devdoc"
-  ];
-
-  patches = lib.optionals stdenv.hostPlatform.isDarwin [
-    ./pygobject-2.0-fix-darwin.patch
-    (fetchpatch {
-      url = "https://github.com/macports/macports-ports/raw/f2975d5bbbc2459c661905c5a850cc661fa32f55/python/py-gobject/files/py-gobject-dynamic_lookup-11.patch";
-      sha256 = "sha256-mtlyu+La3+iC5iQAmVJzDA5E35XGaRQy/EKXzvrWRCg=";
-      extraPrefix = "";
-    })
-  ];
-
-  configureFlags = [ "--disable-introspection" ];
-
-  nativeBuildInputs = [ pkg-config ];
-  buildInputs = [ glib ];
-
-  # in a "normal" setup, pygobject and pygtk are installed into the
-  # same site-packages: we need a pth file for both. pygtk.py would be
-  # used to select a specific version, in our setup it should have no
-  # effect, but we leave it in case somebody expects and calls it.
-  postInstall = lib.optionalString (!isPy3k) ''
-    mv $out/${python.sitePackages}/{pygtk.pth,${pname}-${version}.pth}
-
-    # Prevent wrapping of codegen files as these are meant to be
-    # executed by the python program
-    chmod a-x $out/share/pygobject/*/codegen/*.py
-  '';
-
-  meta = {
-    homepage = "https://pygobject.readthedocs.io/";
-    description = "Python bindings for GLib";
-    license = lib.licenses.gpl2;
-    maintainers = [ ];
-  };
-}
diff --git a/pkgs/development/python2-modules/pygobject/pygobject-2.0-fix-darwin.patch b/pkgs/development/python2-modules/pygobject/pygobject-2.0-fix-darwin.patch
deleted file mode 100644
index 7fef05262f4d..000000000000
--- a/pkgs/development/python2-modules/pygobject/pygobject-2.0-fix-darwin.patch
+++ /dev/null
@@ -1,88 +0,0 @@
---- a/gio/unix-types.defs
-+++ b/gio/unix-types.defs
-@@ -7,18 +7,6 @@
-   (gtype-id "G_TYPE_UNIX_CONNECTION")
- )
- 
--(define-object DesktopAppInfo
--  (docstring
--  "DesktopAppInfo(desktop_id) -> gio.unix.DesktopAppInfo\n\n"
--  "gio.Unix.DesktopAppInfo is an implementation of gio.AppInfo\n"
--  "based on desktop files."
--  )
--  (in-module "giounix")
--  (parent "GObject")
--  (c-name "GDesktopAppInfo")
--  (gtype-id "G_TYPE_DESKTOP_APP_INFO")
--)
--
- (define-object FDMessage
-   (in-module "giounix")
-   (parent "GSocketControlMessage")
---- a/gio/unix.defs
-+++ b/gio/unix.defs
-@@ -32,54 +32,6 @@
- 
- 
- 
--;; From gdesktopappinfo.h
--
--(define-function desktop_app_info_get_type
--  (c-name "g_desktop_app_info_get_type")
--  (return-type "GType")
--)
--
--(define-function desktop_app_info_new_from_filename
--  (c-name "g_desktop_app_info_new_from_filename")
--  (return-type "GDesktopAppInfo*")
--  (parameters
--    '("const-char*" "filename")
--  )
--)
--
--(define-function g_desktop_app_info_new_from_keyfile
--  (c-name "g_desktop_app_info_new_from_keyfile")
--  (return-type "GDesktopAppInfo*")
--  (parameters
--    '("GKeyFile*" "key_file")
--  )
--)
--
--(define-function desktop_app_info_new
--  (c-name "g_desktop_app_info_new")
--  (is-constructor-of "GDesktopAppInfo")
--  (return-type "GDesktopAppInfo*")
--  (parameters
--    '("const-char*" "desktop_id")
--  )
--)
--
--(define-method get_is_hidden
--  (of-object "GDesktopAppInfo")
--  (c-name "g_desktop_app_info_get_is_hidden")
--  (return-type "gboolean")
--)
--
--(define-function desktop_app_info_set_desktop_env
--  (c-name "g_desktop_app_info_set_desktop_env")
--  (return-type "none")
--  (parameters
--    '("const-char*" "desktop_env")
--  )
--)
--
--
--
- ;; From gunixfdmessage.h
- 
- (define-function g_unix_fd_message_get_type
---- a/gio/unix.override
-+++ b/gio/unix.override
-@@ -24,7 +24,6 @@
- #define NO_IMPORT_PYGOBJECT
- #include <pygobject.h>
- #include <gio/gio.h>
--#include <gio/gdesktopappinfo.h>
- #include <gio/gunixinputstream.h>
- #include <gio/gunixmounts.h>
- #include <gio/gunixoutputstream.h>
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 1252de7b1f14..db52f40d06ef 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -353,6 +353,7 @@ mapAliases {
   pymicro-vad = throw "'pymicro-vad' was removed because Home Assistant switched to 'pysilero-vad'"; # added 2026-01-08
   PyMVGLive = throw "'PyMVGLive' has been renamed to/replaced by 'pymvglive'"; # Converted to throw 2025-10-29
   pymyq = throw "'pymyq' has been renamed to/replaced by 'python-myq'"; # Converted to throw 2025-10-29
+  pyobject = throw "'pyobject' has been removed because it was only supporting python 2"; # Added 2026-01-24
   pyownet = throw "pyownet was removed because Home Assistant switched to aio-ownet"; # added 2025-10-31
   pypcap = throw "pypcap has been removed because it is broken and unmaintained upstream."; # added 2025-06-18
   pyqldb = throw "pyqldb has been removed, because the underlying service is reaching end of support"; # added 2025-07-30
diff --git a/pkgs/top-level/python2-packages.nix b/pkgs/top-level/python2-packages.nix
index 86647bbc016f..6bc5a5bbd9a8 100644
--- a/pkgs/top-level/python2-packages.nix
+++ b/pkgs/top-level/python2-packages.nix
@@ -51,8 +51,6 @@ with super;
     inherit (pkgs.buildPackages) meson;
   };
 
-  pygobject2 = callPackage ../development/python2-modules/pygobject { };
-
   pyparsing = callPackage ../development/python2-modules/pyparsing { };
 
   pytest = pytest_4;