diff --git a/nixos/doc/manual/release-notes/rl-2411.section.md b/nixos/doc/manual/release-notes/rl-2411.section.md
index eb3aa5a43472..8f19bcb823d3 100644
--- a/nixos/doc/manual/release-notes/rl-2411.section.md
+++ b/nixos/doc/manual/release-notes/rl-2411.section.md
@@ -217,6 +217,9 @@
 
 - The logrotate service has received hardening and now requires enabling `allowNetworking`, if logrotate needs to access the network.
 
+- qBittorrent has been updated to major version 5, which drops support for Qt 5.
+  The `qbittorrent-qt5` package has been removed.
+
 - The fcgiwrap module now allows multiple instances running as distinct users.
   The option `services.fgciwrap` now takes an attribute set of the
   configuration of each individual instance.
diff --git a/pkgs/applications/networking/p2p/qbittorrent/default.nix b/pkgs/applications/networking/p2p/qbittorrent/default.nix
index c9ff19468745..e542dabc6dae 100644
--- a/pkgs/applications/networking/p2p/qbittorrent/default.nix
+++ b/pkgs/applications/networking/p2p/qbittorrent/default.nix
@@ -28,15 +28,14 @@ let
 in
 stdenv.mkDerivation rec {
   pname = "qbittorrent"
-    + lib.optionalString (guiSupport && qtVersion == "5") "-qt5"
     + lib.optionalString (!guiSupport) "-nox";
-  version = "4.6.7";
+  version = "5.0.0";
 
   src = fetchFromGitHub {
     owner = "qbittorrent";
     repo = "qBittorrent";
     rev = "release-${version}";
-    hash = "sha256-vUC8YIuyoGnl46FajfJG/XFXG+2lM9EaHWl2Hfo3T7c=";
+    hash = "sha256-iwqJaRfwJTL6SimWTNqqqFPXxSKrgo6whYY70llZyGs";
   };
 
   nativeBuildInputs = [
@@ -62,9 +61,7 @@ stdenv.mkDerivation rec {
     python3
   ];
 
-  cmakeFlags = lib.optionals (qtVersion == "6") [
-    "-DQT6=ON"
-  ] ++ lib.optionals (!guiSupport) [
+  cmakeFlags = lib.optionals (!guiSupport) [
     "-DGUI=OFF"
     "-DSYSTEMD=ON"
     "-DSYSTEMD_SERVICES_INSTALL_DIR=${placeholder "out"}/lib/systemd/system"
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index a24730771cf1..8789745cdfce 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -1319,6 +1319,7 @@ mapAliases {
 
   ### Q ###
 
+  qbittorrent-qt5 = throw "'qbittorrent-qt5' has been removed as qBittorrent 5 dropped support for Qt 5. Please use 'qbittorrent'"; # Added 2024-09-30
   qcsxcad = libsForQt5.qcsxcad; # Added 2020-11-05
   qtcreator-qt6 = throw "'qtcreator-qt6' has been renamed to/replaced by 'qtcreator', since qt5 version has been removed"; # Added 2023-07-25
   qflipper = qFlipper; # Added 2022-02-11
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 288564a842f7..28e9a7d37f27 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -32291,9 +32291,6 @@ with pkgs;
     inherit (darwin.apple_sdk.frameworks) Cocoa;
   };
   qbittorrent-nox = qbittorrent.override { guiSupport = false; };
-  qbittorrent-qt5 = libsForQt5.callPackage ../applications/networking/p2p/qbittorrent {
-    inherit (darwin.apple_sdk.frameworks) Cocoa;
-  };
 
   qcad = libsForQt5.callPackage ../applications/misc/qcad { };