diff --git a/pkgs/development/python-modules/aioquic-mitmproxy/default.nix b/pkgs/development/python-modules/aioquic-mitmproxy/default.nix
deleted file mode 100644
index 75ccd6072741..000000000000
--- a/pkgs/development/python-modules/aioquic-mitmproxy/default.nix
+++ /dev/null
@@ -1,56 +0,0 @@
-{ lib
-, buildPythonPackage
-, certifi
-, cryptography
-, fetchFromGitHub
-, pylsqpack
-, pyopenssl
-, pytestCheckHook
-, pythonOlder
-, service-identity
-, setuptools
-, wheel
-}:
-
-buildPythonPackage rec {
-  pname = "aioquic-mitmproxy";
-  version = "0.9.21.1";
-  pyproject = true;
-
-  disabled = pythonOlder "3.8";
-
-  src = fetchFromGitHub {
-    owner = "meitinger";
-    repo = "aioquic_mitmproxy";
-    rev = "refs/tags/${version}";
-    hash = "sha256-eD3eICE9jS1jyqMgWwcv6w3gkR0EyGcKwgSXhasXNeA=";
-  };
-
-  nativeBuildInputs = [
-    setuptools
-    wheel
-  ];
-
-  propagatedBuildInputs = [
-    certifi
-    cryptography
-    pylsqpack
-    pyopenssl
-    service-identity
-  ];
-
-  nativeCheckInputs = [
-    pytestCheckHook
-  ];
-
-  pythonImportsCheck = [
-    "aioquic"
-  ];
-
-  meta = with lib; {
-    description = "QUIC and HTTP/3 implementation in Python";
-    homepage = "https://github.com/meitinger/aioquic_mitmproxy";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ fab ];
-  };
-}
diff --git a/pkgs/development/python-modules/mitmproxy/default.nix b/pkgs/development/python-modules/mitmproxy/default.nix
index 085078429cd5..283208e3500e 100644
--- a/pkgs/development/python-modules/mitmproxy/default.nix
+++ b/pkgs/development/python-modules/mitmproxy/default.nix
@@ -3,8 +3,9 @@
 , fetchFromGitHub
 , buildPythonPackage
 , pythonOlder
+, pythonRelaxDepsHook
   # Mitmproxy requirements
-, aioquic-mitmproxy
+, aioquic
 , asgiref
 , blinker
 , brotli
@@ -56,8 +57,16 @@ buildPythonPackage rec {
     hash = "sha256-BO7oQ4TVuZ4dCtROq2M24V6HVo0jzyBdQfb67dYA07U=";
   };
 
+  nativeBuildInputs = [
+    pythonRelaxDepsHook
+  ];
+
+  pythonRelaxDeps = [
+    "aioquic"
+  ];
+
   propagatedBuildInputs = [
-    aioquic-mitmproxy
+    aioquic
     asgiref
     blinker
     brotli
@@ -109,22 +118,14 @@ buildPythonPackage rec {
     "test_get_version"
     # https://github.com/mitmproxy/mitmproxy/commit/36ebf11916704b3cdaf4be840eaafa66a115ac03
     # Tests require terminal
-    "test_integration"
+    "test_commands_exist"
     "test_contentview_flowview"
     "test_flowview"
-    # ValueError: Exceeds the limit (4300) for integer string conversion
-    "test_roundtrip_big_integer"
-    "test_wireguard"
-    "test_commands_exist"
+    "test_integration"
     "test_statusbar"
-    # AssertionError: Playbook mismatch!
-    "test_untrusted_cert"
-    "test_mitmproxy_ca_is_untrusted"
-  ];
-
-  disabledTestPaths = [
-    # teardown of half the tests broken
-    "test/mitmproxy/addons/test_onboarding.py"
+    # FileNotFoundError: [Errno 2] No such file or directory
+    # likely wireguard is also not working in the sandbox
+    "test_wireguard"
   ];
 
   dontUsePytestXdist = true;
@@ -136,6 +137,6 @@ buildPythonPackage rec {
     homepage = "https://mitmproxy.org/";
     changelog = "https://github.com/mitmproxy/mitmproxy/blob/${version}/CHANGELOG.md";
     license = licenses.mit;
-    maintainers = with maintainers; [ kamilchm SuperSandro2000 ];
+    maintainers = with maintainers; [ SuperSandro2000 ];
   };
 }
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 067e702b76d5..e2baccf5192b 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -39,6 +39,7 @@ mapAliases ({
   aioh2 = throw "aioh2 has been removed because it is abandoned and broken."; # Added 2022-03-30
   aionotify = throw "aionotify has been removed because is unmaintained and incompatible with python3.11."; # Added 2023-10-27
   aiosenseme = throw "aiosenseme has been removed, because it does no longer work with the latest firmware and has become unmaintained"; # Added 2023-07-05
+  aioquic-mitmproxy = throw "aioquic-mitmproxy has been removed because mitmproxy no longer uses it"; # Added 2024-01-16
   amazon_kclpy = amazon-kclpy; # added 2023-08-08
   ansible-base = throw "ansible-base has been removed, because it is end of life"; # added 2022-03-30
   ansible-doctor = throw "ansible-doctor has been promoted to a top-level attribute"; # Added 2023-05-16
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 9ddfadf07d4a..cc62743493f2 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -349,8 +349,6 @@ self: super: with self; {
 
   aioquic = callPackage ../development/python-modules/aioquic { };
 
-  aioquic-mitmproxy = callPackage ../development/python-modules/aioquic-mitmproxy { };
-
   aiorecollect = callPackage ../development/python-modules/aiorecollect { };
 
   aioredis = callPackage ../development/python-modules/aioredis { };