diff --git a/pkgs/development/python-modules/cyclonedds-python/default.nix b/pkgs/development/python-modules/cyclonedds-python/default.nix
new file mode 100644
index 000000000000..e23214d57dfe
--- /dev/null
+++ b/pkgs/development/python-modules/cyclonedds-python/default.nix
@@ -0,0 +1,53 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+
+  cyclonedds,
+  setuptools,
+  rich-click,
+
+  pytestCheckHook,
+  pytest-mock,
+  pytest-cov-stub,
+}:
+
+buildPythonPackage rec {
+  pname = "cyclonedds-python";
+  version = "0.10.5";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "eclipse-cyclonedds";
+    repo = "cyclonedds-python";
+    rev = "refs/tags/${version}";
+    hash = "sha256-MN3Z5gqsD+cr5Awmsia9+uCHL/a2KQP2uMS13rVc1Hw=";
+  };
+
+  postPatch = ''
+    substituteInPlace pyproject.toml \
+        --replace-fail "pytest-cov" ""
+  '';
+
+  build-system = [ setuptools ];
+
+  buildInputs = [ cyclonedds ];
+
+  dependencies = [ rich-click ];
+
+  env.CYCLONEDDS_HOME = "${cyclonedds.out}";
+
+  nativeCheckInputs = [
+    pytestCheckHook
+    pytest-mock
+    pytest-cov-stub
+  ];
+
+  meta = {
+    description = "Python binding for Eclipse Cyclone DDS";
+    homepage = "https://github.com/eclipse-cyclonedds/cyclonedds-python";
+    changelog = "https://github.com/eclipse-cyclonedds/cyclonedds-python/releases/tag/${version}";
+    license = lib.licenses.epl20;
+    maintainers = with lib.maintainers; [ kvik ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 4c04ff4a3740..a36ab65d7b2e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -2755,6 +2755,8 @@ self: super: with self; {
 
   cycler = callPackage ../development/python-modules/cycler { };
 
+  cyclonedds-python = callPackage ../development/python-modules/cyclonedds-python { };
+
   cyclonedx-python-lib = callPackage ../development/python-modules/cyclonedx-python-lib { };
 
   cyclopts = callPackage ../development/python-modules/cyclopts { };