diff --git a/pkgs/by-name/dt/dtc/package.nix b/pkgs/by-name/dt/dtc/package.nix
index 527ffe873bb2..ed41487a81b2 100644
--- a/pkgs/by-name/dt/dtc/package.nix
+++ b/pkgs/by-name/dt/dtc/package.nix
@@ -11,6 +11,7 @@
   which,
   pythonSupport ? false,
   python ? null,
+  replaceVars,
   swig,
   libyaml,
 }:
@@ -38,7 +39,15 @@ stdenv.mkDerivation (finalAttrs: {
       url = "https://github.com/dgibson/dtc/commit/ce1d8588880aecd7af264e422a16a8b33617cef7.patch";
       hash = "sha256-t1CxKnbCXUArtVcniAIdNvahOGXPbYhPCZiTynGLvfo=";
     })
-  ];
+  ]
+  ++
+    lib.optional pythonSupport
+      # Make Meson use our Python version, not the one it was built with itself
+      (
+        replaceVars ./python-path.patch {
+          python_bin = lib.getExe python;
+        }
+      );
 
   env.SETUPTOOLS_SCM_PRETEND_VERSION = finalAttrs.version;
 
diff --git a/pkgs/by-name/dt/dtc/python-path.patch b/pkgs/by-name/dt/dtc/python-path.patch
new file mode 100644
index 000000000000..6163dc0b294d
--- /dev/null
+++ b/pkgs/by-name/dt/dtc/python-path.patch
@@ -0,0 +1,12 @@
+diff --git a/meson.build b/meson.build
+index 310699f..4e2b8a4 100644
+--- a/meson.build
++++ b/meson.build
+@@ -48,7 +48,7 @@ if not valgrind.found()
+ endif
+ 
+ py = import('python')
+-py = py.find_installation(required: get_option('python'))
++py = py.find_installation('@python_bin@', required: get_option('python'))
+ swig = find_program('swig', required: get_option('python'))
+ pylibfdt_enabled = not meson.is_cross_build() and py.found() and swig.found() ? true : false