diff --git a/pkgs/development/python-modules/pyrdfa3/default.nix b/pkgs/development/python-modules/pyrdfa3/default.nix
index 97768e7fed50..610eaa39bd7e 100644
--- a/pkgs/development/python-modules/pyrdfa3/default.nix
+++ b/pkgs/development/python-modules/pyrdfa3/default.nix
@@ -1,6 +1,7 @@
 { lib
 , buildPythonPackage
 , fetchPypi
+, fetchpatch
 , isPy27
 , rdflib
 , html5lib
@@ -17,6 +18,14 @@ buildPythonPackage rec {
     sha256 = "sha256-FXZjqSuH3zRbb2m94jXf9feXiRYI4S/h5PqNrWhxMa4=";
   };
 
+  patches = [
+    (fetchpatch {
+      name = "CVE-2022-4396.patch";
+      url = "https://github.com/RDFLib/pyrdfa3/commit/ffd1d62dd50d5f4190013b39cedcdfbd81f3ce3e.patch";
+      hash = "sha256-prRrOwylYcEqKLr/8LIpyJ5Yyt+6+HTUqH5sQXU8tqc=";
+    })
+  ];
+
   postPatch = ''
     substituteInPlace setup.py \
       --replace "'html = pyRdfa.rdflibparsers:StructuredDataParser'" "'html = pyRdfa.rdflibparsers:StructuredDataParser'," \