diff --git a/pkgs/by-name/pe/peru/package.nix b/pkgs/by-name/pe/peru/package.nix
index 1fb1543b5e34..1c632f013ed9 100644
--- a/pkgs/by-name/pe/peru/package.nix
+++ b/pkgs/by-name/pe/peru/package.nix
@@ -9,8 +9,6 @@ python3Packages.buildPythonApplication rec {
   version = "1.3.4";
   pyproject = true;
 
-  disabled = python3Packages.pythonOlder "3.5";
-
   src = fetchFromGitHub {
     owner = "buildinspace";
     repo = "peru";
diff --git a/pkgs/development/python-modules/pathlib2/default.nix b/pkgs/development/python-modules/pathlib2/default.nix
index afb3a3af3a58..f922218f9142 100644
--- a/pkgs/development/python-modules/pathlib2/default.nix
+++ b/pkgs/development/python-modules/pathlib2/default.nix
@@ -3,9 +3,6 @@
   buildPythonPackage,
   fetchPypi,
   six,
-  pythonOlder,
-  scandir ? null,
-  typing,
 }:
 
 buildPythonPackage rec {
@@ -20,10 +17,6 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [
     six
-  ]
-  ++ lib.optionals (pythonOlder "3.5") [
-    scandir
-    typing
   ];
 
   meta = {
diff --git a/pkgs/development/python-modules/remctl/default.nix b/pkgs/development/python-modules/remctl/default.nix
index 3475943d4269..908334b1cfe1 100644
--- a/pkgs/development/python-modules/remctl/default.nix
+++ b/pkgs/development/python-modules/remctl/default.nix
@@ -1,9 +1,6 @@
 {
-  lib,
   buildPythonPackage,
-  pythonOlder,
   remctl-c, # remctl from pkgs, not from pythonPackages
-  typing,
 }:
 
 buildPythonPackage {
@@ -17,6 +14,4 @@ buildPythonPackage {
   setSourceRoot = "sourceRoot=$(echo */python)";
 
   buildInputs = [ remctl-c ];
-
-  propagatedBuildInputs = lib.optionals (pythonOlder "3.5") [ typing ];
 }
diff --git a/pkgs/development/python-modules/uranium/default.nix b/pkgs/development/python-modules/uranium/default.nix
index 96ce10f8da79..91bd77e10dc2 100644
--- a/pkgs/development/python-modules/uranium/default.nix
+++ b/pkgs/development/python-modules/uranium/default.nix
@@ -12,7 +12,6 @@
   cryptography,
   doxygen,
   gettext,
-  pythonOlder,
 }:
 
 buildPythonPackage rec {
@@ -27,8 +26,6 @@ buildPythonPackage rec {
     hash = "sha256-SE9xqrloPXIRTJiiqUdRKFmb4c0OjmJK5CMn6VXMFmk=";
   };
 
-  disabled = pythonOlder "3.5.0";
-
   buildInputs = [
     python
     gettext