diff --git a/pkgs/development/interpreters/luajit/openresty.nix b/pkgs/development/interpreters/luajit/openresty.nix
index c8bf0cfd50e8..2321f87f524e 100644
--- a/pkgs/development/interpreters/luajit/openresty.nix
+++ b/pkgs/development/interpreters/luajit/openresty.nix
@@ -15,5 +15,17 @@ callPackage ./default.nix rec {
     hash = "sha256-SICmM+/dvp/36UAWAH0l7D938iFDimnoKBOjlOodrCY=";
   };
 
+  extraMeta = {
+    badPlatforms = [
+      "loongarch64-linux" # See https://github.com/LuaJIT/LuaJIT/issues/1278
+      "riscv64-linux" # See https://github.com/LuaJIT/LuaJIT/issues/628
+      # 64-bit POWER (LE and BE, either ELF ABI version on the latter) *is* supported, but ELFv1 powerpc64-linux has an
+      # issue with memory allocation
+      # https://github.com/openresty/luajit2/issues/258
+      # Both BE ABI versions use the same double though, so would have to inspect stdenv to differentiate.
+      "powerpc64-linux"
+    ];
+  };
+
   inherit self passthruFun;
 }