diff --git a/pkgs/development/libraries/unicorn/default.nix b/pkgs/development/libraries/unicorn/default.nix
index 0a760c07a97e..57983537ad14 100644
--- a/pkgs/development/libraries/unicorn/default.nix
+++ b/pkgs/development/libraries/unicorn/default.nix
@@ -6,13 +6,13 @@
 
 stdenv.mkDerivation rec {
   pname = "unicorn";
-  version = "1.0.3";
+  version = "2.0.0-rc4";
 
   src = fetchFromGitHub {
     owner = "unicorn-engine";
     repo = pname;
     rev = version;
-    sha256 = "079azb1df4nwsnsck36b200rnf03aqilw30h3fiaqi1ixash957k";
+    sha256 = "sha256-dNBebXp8HVmmY1RVRYuRFoJ3PStCf4taNTeYKi2lhQM=";
   };
 
   nativeBuildInputs = [ pkg-config cmake ];
diff --git a/pkgs/development/python-modules/manticore/default.nix b/pkgs/development/python-modules/manticore/default.nix
index 9e0938fb1486..0c36f2cc6cc6 100644
--- a/pkgs/development/python-modules/manticore/default.nix
+++ b/pkgs/development/python-modules/manticore/default.nix
@@ -1,38 +1,46 @@
 { lib
 , buildPythonPackage
-, fetchFromGitHub
 , capstone
 , crytic-compile
+, fetchFromGitHub
+, intervaltree
 , ply
 , prettytable
+, protobuf
 , pyelftools
 , pyevmasm
 , pysha3
+, pytestCheckHook
+, pythonOlder
 , pyyaml
 , rlp
 , stdenv
 , unicorn
 , wasm
 , yices
-, pytestCheckHook
 , z3
 }:
 
 buildPythonPackage rec {
   pname = "manticore";
-  version = "0.3.5";
+  version = "0.3.6";
+  format = "setuptools";
+
+  disabled = pythonOlder "3.7";
 
   src = fetchFromGitHub {
     owner = "trailofbits";
     repo = "manticore";
     rev = version;
-    sha256 = "0z2nhfcraa5dx6srbrw8s11awh2la0x7d88yw9in8g548nv6qa69";
+    sha256 = "sha256-L112YwrBcdcLBeBsPLWt3C57u2WDvGLq50EzW9ojdyg=";
   };
 
   propagatedBuildInputs = [
     crytic-compile
+    intervaltree
     ply
     prettytable
+    protobuf
     pyevmasm
     pysha3
     pyyaml
@@ -49,22 +57,29 @@ buildPythonPackage rec {
     sed -ie s/z3-solver// setup.py
   '';
 
-  checkInputs = [ pytestCheckHook ];
-  preCheck = "export PATH=${yices}/bin:${z3}/bin:$PATH";
-  pytestFlagsArray = [
-    "--ignore=tests/ethereum" # TODO: enable when solc works again
-    "--ignore=tests/ethereum_bench"
-  ] ++ lib.optionals (!stdenv.isLinux) [
-    "--ignore=tests/native"
-    "--ignore=tests/other/test_locking.py"
-    "--ignore=tests/other/test_state_introspection.py"
+  checkInputs = [
+    pytestCheckHook
   ];
+
+  preCheck = ''
+    export PATH=${yices}/bin:${z3}/bin:$PATH
+  '';
+
+  disabledTestPaths = [
+    "tests/ethereum" # Enable when solc works again
+    "tests/ethereum_bench"
+  ] ++ lib.optionals (!stdenv.isLinux) [
+    "tests/native"
+    "tests/other/test_locking.py"
+    "tests/other/test_state_introspection.py"
+  ];
+
   disabledTests = [
-    # failing tests
+    # Failing tests
     "test_chmod"
     "test_timeout"
     "test_wasm_main"
-    # slow tests
+    # Slow tests
     "testmprotectFailSymbReading"
     "test_ConstraintsForking"
     "test_resume"
@@ -97,6 +112,13 @@ buildPythonPackage rec {
     "test_implicit_call"
     "test_trace"
     "test_plugin"
+    # Tests are failing with latest unicorn
+    "Aarch64UnicornInstructions"
+    "test_integration_resume"
+  ];
+
+  pythonImportsCheck = [
+    "manticore"
   ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/multiprocess/default.nix b/pkgs/development/python-modules/multiprocess/default.nix
index df304efb9199..491aa131bb59 100644
--- a/pkgs/development/python-modules/multiprocess/default.nix
+++ b/pkgs/development/python-modules/multiprocess/default.nix
@@ -1,22 +1,36 @@
-{ lib, buildPythonPackage, fetchPypi, dill }:
+{ lib
+, buildPythonPackage
+, dill
+, fetchFromGitHub
+}:
 
 buildPythonPackage rec {
   pname = "multiprocess";
-  version = "0.70.9";
+  version = "0.70.12.2";
+  format = "setuptools";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "9fd5bd990132da77e73dec6e9613408602a4612e1d73caf2e2b813d2b61508e5";
+  src = fetchFromGitHub {
+    owner = "uqfoundation";
+    repo = pname;
+    rev = "multiprocess-${version}";
+    sha256 = "1npikdgj0qriqj384vg22qgq2xqylypk67sx1qfmdzvk6c4iyg0w";
   };
 
-  propagatedBuildInputs = [ dill ];
+  propagatedBuildInputs = [
+    dill
+  ];
 
   # Python-version dependent tests
   doCheck = false;
 
+  pythonImportsCheck = [
+    "multiprocess"
+  ];
+
   meta = with lib; {
-    description = "Better multiprocessing and multithreading in python";
+    description = "Multiprocessing and multithreading in Python";
     homepage = "https://github.com/uqfoundation/multiprocess";
     license = licenses.bsd3;
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/qiling/default.nix b/pkgs/development/python-modules/qiling/default.nix
index 61787548f846..3576f5b73660 100644
--- a/pkgs/development/python-modules/qiling/default.nix
+++ b/pkgs/development/python-modules/qiling/default.nix
@@ -1,33 +1,43 @@
 { lib
 , buildPythonPackage
-, fetchPypi
 , capstone
-, unicorn
-, pefile
-, python-registry
-, keystone-engine
-, pyelftools
+, fetchFromGitHub
+, fetchPypi
 , gevent
+, keystone-engine
+, multiprocess
+, pefile
+, pyelftools
+, python-registry
+, unicorn
 }:
+
 buildPythonPackage rec {
   pname = "qiling";
-  version = "1.3.0";
+  version = "1.4.0";
+  format = "setuptools";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "084ad706f6803d7de2391eab928ecf4cb3e8d892fd2988666d4791a422d6ab9a";
+    sha256 = "sha256-xUoNHMyGN0G2itVcKLsk+7QKxZdguzyh6OZCqCHNB4Y=";
   };
 
   propagatedBuildInputs = [
     capstone
-    unicorn
-    pefile
-    python-registry
-    keystone-engine
-    pyelftools
     gevent
+    keystone-engine
+    multiprocess
+    pefile
+    pyelftools
+    python-registry
+    unicorn
   ];
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "pefile==2021.5.24" "pefile>=2021.5.24"
+  '';
+
   # Tests are broken (attempt to import a file that tells you not to import it,
   # amongst other things)
   doCheck = false;
diff --git a/pkgs/development/python-modules/unicorn/default.nix b/pkgs/development/python-modules/unicorn/default.nix
index 484f422adf3e..c9043afa85d9 100644
--- a/pkgs/development/python-modules/unicorn/default.nix
+++ b/pkgs/development/python-modules/unicorn/default.nix
@@ -1,10 +1,17 @@
-{ lib, stdenv, buildPythonPackage, setuptools, unicorn-emu }:
+{ lib
+, stdenv
+, buildPythonPackage
+, setuptools
+, unicorn-emu
+}:
 
 buildPythonPackage rec {
   pname = "unicorn";
   version = lib.getVersion unicorn-emu;
+  format = "setuptools";
 
   src = unicorn-emu.src;
+
   sourceRoot = "source/bindings/python";
 
   prePatch = ''
@@ -12,12 +19,21 @@ buildPythonPackage rec {
     ln -s ${unicorn-emu}/lib/libunicorn.a prebuilt/
   '';
 
-  propagatedBuildInputs = [ setuptools ];
+  propagatedBuildInputs = [
+    setuptools
+  ];
+
+  # No tests present
+  doCheck = false;
+
+  pythonImportsCheck = [
+    "unicorn"
+  ];
 
   meta = with lib; {
     description = "Python bindings for Unicorn CPU emulator engine";
     homepage = "https://www.unicorn-engine.org/";
-    license = [ licenses.gpl2 ];
+    license = licenses.gpl2Plus;
     maintainers = with maintainers; [ bennofs ris ];
   };
 }