diff --git a/pkgs/development/libraries/gdk-pixbuf/default.nix b/pkgs/development/libraries/gdk-pixbuf/default.nix
index ea14e2fab2d1..3e11aaf7bc6b 100644
--- a/pkgs/development/libraries/gdk-pixbuf/default.nix
+++ b/pkgs/development/libraries/gdk-pixbuf/default.nix
@@ -73,8 +73,16 @@ stdenv.mkDerivation rec {
   '';
 
   postInstall =
-    # All except one utility seem to be only useful during building.
+    # meson erroneously installs loaders with .dylib extension on Darwin.
+    # Their @rpath has to be replaced before gdk-pixbuf-query-loaders looks at them.
+    stdenv.lib.optionalString stdenv.isDarwin ''
+      for f in $out/${passthru.moduleDir}/*.dylib; do
+          install_name_tool -change @rpath/libgdk_pixbuf-2.0.0.dylib $out/lib/libgdk_pixbuf-2.0.0.dylib $f
+          mv $f ''${f%.dylib}.so
+      done
     ''
+    # All except one utility seem to be only useful during building.
+    + ''
       moveToOutput "bin" "$dev"
       moveToOutput "bin/gdk-pixbuf-thumbnailer" "$out"