diff --git a/pkgs/by-name/in/intel-compute-runtime/package.nix b/pkgs/by-name/in/intel-compute-runtime/package.nix
index cdfc45903c4a..c0fe30683db0 100644
--- a/pkgs/by-name/in/intel-compute-runtime/package.nix
+++ b/pkgs/by-name/in/intel-compute-runtime/package.nix
@@ -39,6 +39,9 @@ stdenv.mkDerivation rec {
     (lib.cmakeFeature "OCL_ICD_VENDORDIR" "${placeholder "out"}/etc/OpenCL/vendors")
     # The install script assumes this path is relative to CMAKE_INSTALL_PREFIX
     (lib.cmakeFeature "CMAKE_INSTALL_LIBDIR" "lib")
+    # disable spectre mitigations (already mitigated in the kernel)
+    # https://bugs.launchpad.net/ubuntu/+source/intel-compute-runtime/+bug/2110131
+    (lib.cmakeBool "NEO_DISABLE_MITIGATIONS" true)
   ];
 
   outputs = [