diff --git a/pkgs/top-level/perl-packages.nix b/pkgs/top-level/perl-packages.nix
index 0110bcdeb1b1..323e892019ba 100644
--- a/pkgs/top-level/perl-packages.nix
+++ b/pkgs/top-level/perl-packages.nix
@@ -33240,9 +33240,10 @@ with self;
       ./scripts/yath test -j $NIX_BUILD_CORES
     '';
 
-    # The t/integration/preload.t test is broken on riscv64
+    # The t/integration/preload.t test is broken on riscv64 & powerpc64
     # https://github.com/Test-More/Test2-Harness/issues/290
-    doCheck = !stdenv.hostPlatform.isRiscV;
+    doCheck =
+      !stdenv.hostPlatform.isRiscV && !(stdenv.hostPlatform.isPower64 && stdenv.hostPlatform.isBigEndian);
 
     propagatedBuildInputs = [
       DataUUID