diff --git a/pkgs/development/python-modules/tlslite-ng/default.nix b/pkgs/development/python-modules/tlslite-ng/default.nix
index 266acc638b8f..450f40234378 100644
--- a/pkgs/development/python-modules/tlslite-ng/default.nix
+++ b/pkgs/development/python-modules/tlslite-ng/default.nix
@@ -2,6 +2,7 @@
   lib,
   buildPythonPackage,
   fetchPypi,
+  pythonAtLeast,
   ecdsa,
 }:
 
@@ -10,6 +11,9 @@ buildPythonPackage rec {
   version = "0.7.6";
   format = "setuptools";
 
+  # https://github.com/tlsfuzzer/tlslite-ng/issues/501
+  disabled = pythonAtLeast "3.12";
+
   src = fetchPypi {
     inherit pname version;
     sha256 = "6ab56f0e9629ce3d807eb528c9112defa9f2e00af2b2961254e8429ca5c1ff00";