diff --git a/pkgs/by-name/xt/xtrlock-pam/package.nix b/pkgs/by-name/xt/xtrlock-pam/package.nix
deleted file mode 100644
index 0136fbc5c287..000000000000
--- a/pkgs/by-name/xt/xtrlock-pam/package.nix
+++ /dev/null
@@ -1,42 +0,0 @@
-{
-  lib,
-  stdenv,
-  fetchFromGitHub,
-  python39,
-  pkg-config,
-  pam,
-  xorg,
-}:
-
-stdenv.mkDerivation {
-  pname = "xtrlock-pam";
-  version = "3.4-post-20150909";
-
-  src = fetchFromGitHub {
-    owner = "aanatoly";
-    repo = "xtrlock-pam";
-    rev = "6f4920fcfff54791c0779057e9efacbbbbc05df6";
-    sha256 = "sha256-TFfs418fpjBrAJNGW8U3jE0K7jQkfL4vCquAViKkXPw=";
-  };
-
-  nativeBuildInputs = [ pkg-config ];
-  buildInputs = [
-    python39
-    pam
-    xorg.libX11
-  ];
-
-  configurePhase = ''
-    substituteInPlace .config/options.py --replace /usr/include/security/pam_appl.h ${pam}/include/security/pam_appl.h
-    substituteInPlace src/xtrlock.c --replace system-local-login xscreensaver
-    python configure --prefix=$out
-  '';
-
-  meta = {
-    homepage = "https://github.com/aanatoly/xtrlock-pam";
-    description = "PAM based X11 screen locker";
-    license = "unknown";
-    maintainers = with lib.maintainers; [ ondt ];
-    platforms = with lib.platforms; linux;
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 6157b05df0af..28a6488a5241 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -1543,6 +1543,7 @@ mapAliases {
   xplayer = throw "xplayer has been removed as the upstream project was archived"; # Added 2024-12-27
   xprite-editor = throw "'xprite-editor' has been removed due to lack of maintenance upstream. Consider using 'pablodraw' or 'aseprite' instead"; # Added 2024-09-14
   xsv = throw "'xsv' has been removed due to lack of upstream maintenance. Please see 'xan' for a maintained alternative";
+  xtrlock-pam = throw "xtrlock-pam has been removed because it is unmaintained for 10 years and doesn't support Python 3.10 or newer"; # Added 2025-01-25
   xulrunner = firefox-unwrapped; # Added 2023-11-03
   xvfb_run = throw "'xvfb_run' has been renamed to/replaced by 'xvfb-run'"; # Converted to throw 2024-10-17
   xwaylandvideobridge = libsForQt5.xwaylandvideobridge; # Added 2024-09-27