diff --git a/pkgs/development/python-modules/aesara/default.nix b/pkgs/development/python-modules/aesara/default.nix
deleted file mode 100644
index d74c96288335..000000000000
--- a/pkgs/development/python-modules/aesara/default.nix
+++ /dev/null
@@ -1,113 +0,0 @@
-{
-  lib,
-  stdenv,
-  buildPythonPackage,
-  cons,
-  cython,
-  etuples,
-  fetchFromGitHub,
-  filelock,
-  hatch-vcs,
-  hatchling,
-  jax,
-  jaxlib,
-  logical-unification,
-  minikanren,
-  numba,
-  numba-scipy,
-  numpy,
-  pytestCheckHook,
-  pythonAtLeast,
-  pythonOlder,
-  scipy,
-  typing-extensions,
-}:
-
-buildPythonPackage rec {
-  pname = "aesara";
-  version = "2.9.4";
-  pyproject = true;
-
-  # Python 3.12 is not supported: https://github.com/aesara-devs/aesara/issues/1520
-  disabled = pythonOlder "3.8" || pythonAtLeast "3.12";
-
-  src = fetchFromGitHub {
-    owner = "aesara-devs";
-    repo = "aesara";
-    rev = "refs/tags/rel-${version}";
-    hash = "sha256-V34uP50TfH6cLU7nWOx+8oXY1QawtaoIaKQpbLnz7eo=";
-  };
-
-  build-system = [
-    cython
-    hatch-vcs
-    hatchling
-  ];
-
-  dependencies = [
-    cons
-    etuples
-    filelock
-    logical-unification
-    minikanren
-    numpy
-    scipy
-    typing-extensions
-  ];
-
-  nativeCheckInputs = [
-    jax
-    jaxlib
-    numba
-    numba-scipy
-    pytestCheckHook
-  ];
-
-  postPatch = ''
-    substituteInPlace pyproject.toml \
-      --replace-fail "--durations=50" "" \
-      --replace-fail "hatch-vcs >=0.3.0,<0.4.0" "hatch-vcs"
-  '';
-
-  preBuild = ''
-    export HOME=$(mktemp -d)
-  '';
-
-  pythonImportsCheck = [ "aesara" ];
-
-  disabledTestPaths = [
-    # Don't run the most compute-intense tests
-    "tests/scan/"
-    "tests/tensor/"
-    "tests/sandbox/"
-    "tests/sparse/sandbox/"
-    # JAX is not available on all platform and often broken
-    "tests/link/jax/"
-
-    # 2024-04-27: The current nixpkgs numba version is too recent and incompatible with aesara 2.9.3
-    "tests/link/numba/"
-  ];
-
-  disabledTests = [
-    # Disable all benchmark tests
-    "test_scan_multiple_output"
-    "test_logsumexp_benchmark"
-
-    # TypeError: exceptions must be derived from Warning, not <class 'NoneType'>
-    "test_api_deprecation_warning"
-    # AssertionError: assert ['Elemwise{Co..._i{0} 0', ...] == ['Elemwise{Co..._i{0} 0', ...]
-    # At index 3 diff: '| |Gemv{inplace} d={0: [0]} 2' != '| |CGemv{inplace} d={0: [0]} 2'
-    "test_debugprint"
-    # ValueError: too many values to unpack (expected 3)
-    "test_ExternalCOp_c_code_cache_version"
-  ];
-
-  meta = with lib; {
-    description = "Python library to define, optimize, and efficiently evaluate mathematical expressions involving multi-dimensional arrays";
-    homepage = "https://github.com/aesara-devs/aesara";
-    changelog = "https://github.com/aesara-devs/aesara/releases/tag/rel-${version}";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ Etjean ];
-    broken = (stdenv.hostPlatform.isLinux && stdenv.hostPlatform.isAarch64);
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 2d21fb54caf4..56a53c488871 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -39,6 +39,7 @@ mapAliases ({
   acoustics = throw "acoustics has been removed because the upstream repository was archived in 2024"; # Added 2024-10-04
   adafruit-nrfutil = throw "adafruit-nrfutil has been promoted to a top-level attribute name: `pkgs.adafruit-nrfutil`."; # Added 2023-11-19
   aeppl = throw "aeppl was removed as it depends on aesara, which is unmaintained"; # added 2025-01-12
+  aesara = throw "aesara was removed as the upstream repository is unmaintained"; # added 2025-01-12
   aioaladdinconnect = throw "aioaladdinconnect has been removed, as the API is supported was obsoleted on 2024-01-24."; # Added 2024-06-07
   aiohttp-isal = throw "aiohttp-isal has been removed, as it has been archived and replace by aiohttp-fast-zlib"; # Added 2024-08-11
   aiohttp-zlib-ng = throw "aiohttp-zlib-ng has been removed, as it has been archived and replaced by aiohttp-fast-zlib"; # Added 2024-11-14
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index ddf5e3caa67b..747533a56216 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -101,8 +101,6 @@ self: super: with self; {
 
   aerosandbox = callPackage ../development/python-modules/aerosandbox { };
 
-  aesara = callPackage ../development/python-modules/aesara { };
-
   aesedb = callPackage ../development/python-modules/aesedb { };
 
   aetcd = callPackage ../development/python-modules/aetcd { };