diff --git a/pkgs/development/python-modules/scipp/default.nix b/pkgs/development/python-modules/scipp/default.nix
new file mode 100644
index 000000000000..2980d84d4908
--- /dev/null
+++ b/pkgs/development/python-modules/scipp/default.nix
@@ -0,0 +1,107 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+
+  # build-system
+  scikit-build-core,
+  setuptools,
+  setuptools-scm,
+
+  # nativeBuildInputs
+  cmake,
+  ninja,
+
+  # dependencies
+  numpy,
+  units-llnl,
+
+  # buildInputs
+  boost,
+  eigen,
+  gtest,
+  pybind11,
+  tbb_2022_0,
+
+  # tests
+  pytestCheckHook,
+  scipy,
+  beautifulsoup4,
+  ipython,
+  matplotlib,
+  pandas,
+  numba,
+  xarray,
+  h5py,
+  hypothesis,
+}:
+
+buildPythonPackage rec {
+  pname = "scipp";
+  version = "25.05.1";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "scipp";
+    repo = "Scipp";
+    # https://github.com/scipp/scipp/pull/3722
+    tag = version;
+    hash = "sha256-AanXb+nF/YIZFuzG5UnoNPX97WScfPKuoSBY18uYt9k=";
+  };
+  env = {
+    SKIP_CONAN = "true";
+  };
+
+  build-system = [
+    scikit-build-core
+    setuptools
+    setuptools-scm
+  ];
+
+  nativeBuildInputs = [
+    cmake
+    ninja
+  ];
+  dontUseCmakeConfigure = true;
+
+  dependencies = [
+    numpy
+  ];
+
+  buildInputs = [
+    boost
+    eigen
+    gtest
+    pybind11
+    units-llnl.passthru.top-level
+    tbb_2022_0
+  ];
+
+  nativeCheckInputs = [
+    pytestCheckHook
+    scipy
+    beautifulsoup4
+    ipython
+    matplotlib
+    pandas
+    numba
+    xarray
+    h5py
+    hypothesis
+  ];
+  pytestFlagsArray = [
+    # See https://github.com/scipp/scipp/issues/3721
+    "--hypothesis-profile=ci"
+  ];
+
+  pythonImportsCheck = [
+    "scipp"
+  ];
+
+  meta = {
+    description = "Multi-dimensional data arrays with labeled dimensions";
+    homepage = "https://scipp.github.io";
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ doronbehar ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 5d4d3954d3c8..209144e104ef 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -15829,6 +15829,8 @@ self: super: with self; {
 
   scim2-tester = callPackage ../development/python-modules/scim2-tester { };
 
+  scipp = callPackage ../development/python-modules/scipp { };
+
   scipy = callPackage ../development/python-modules/scipy { };
 
   scmrepo = callPackage ../development/python-modules/scmrepo { };