diff --git a/pkgs/development/python-modules/pysam/default.nix b/pkgs/development/python-modules/pysam/default.nix
index 31e01e83dbf6..41cdcad20385 100644
--- a/pkgs/development/python-modules/pysam/default.nix
+++ b/pkgs/development/python-modules/pysam/default.nix
@@ -15,7 +15,7 @@
 
 buildPythonPackage rec {
   pname   = "pysam";
-  version = "0.16.0.1";
+  version = "0.17.0";
 
   # Fetching from GitHub instead of PyPi cause the 0.13 src release on PyPi is
   # missing some files which cause test failures.
@@ -24,7 +24,7 @@ buildPythonPackage rec {
     owner = "pysam-developers";
     repo = "pysam";
     rev = "v${version}";
-    sha256 = "168bwwm8c2k22m7paip8q0yajyl7xdxgnik0bgjl7rhqg0majz0f";
+    sha256 = "sha256-RDeBq6pwBGCBNIn8YOPQr96GuL6FKEYeLAPQD6XN0iE=";
   };
 
   nativeBuildInputs = [ samtools ];