diff --git a/pkgs/development/python-modules/can-isotp/default.nix b/pkgs/development/python-modules/can-isotp/default.nix
new file mode 100644
index 000000000000..90dba000d395
--- /dev/null
+++ b/pkgs/development/python-modules/can-isotp/default.nix
@@ -0,0 +1,51 @@
+{
+  lib,
+  stdenv,
+  buildPythonPackage,
+  fetchFromGitHub,
+  pythonOlder,
+  pytestCheckHook,
+  setuptools,
+}:
+
+buildPythonPackage rec {
+  pname = "can-isotp";
+  version = "2.0.6";
+  pyproject = true;
+
+  disabled = pythonOlder "3.7";
+
+  src = fetchFromGitHub {
+    owner = "pylessard";
+    repo = "python-can-isotp";
+    rev = "refs/tags/v${version}";
+    hash = "sha256-wfZMVfLBdYkFbb0DiDWmGaraykJ/QL64Zkl2/nBu4lY=";
+  };
+
+  build-system = [ setuptools ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
+
+  disabledTestPaths = [
+    # we don't support socket tests
+    "test/test_can_stack.py"
+    "test/test_layer_vs_socket.py"
+    "test/test_socket.py"
+
+    # behaves inconsistently due to timing
+    "test/test_transport_layer.py"
+    "test/test_helper_classes.py"
+  ];
+
+  pythonImportsCheck = [ "isotp" ];
+
+  meta = with lib; {
+    description = "Python package that provides support for ISO-TP (ISO-15765) protocol";
+    homepage = "https://github.com/pylessard/python-can-isotp";
+    changelog = "https://github.com/pylessard/python-can-isotp/releases/tag/v${version}";
+    license = licenses.mit;
+    maintainers = with maintainers; [
+      jacobkoziej
+    ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index bb45317ec90d..319dd25f521b 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1977,6 +1977,8 @@ self: super: with self; {
 
   camel-converter = callPackage ../development/python-modules/camel-converter { };
 
+  can-isotp = callPackage ../development/python-modules/can-isotp { };
+
   canals = callPackage ../development/python-modules/canals { };
 
   canmatrix = callPackage ../development/python-modules/canmatrix { };