diff --git a/pkgs/by-name/or/orthanc-framework/package.nix b/pkgs/by-name/or/orthanc-framework/package.nix
index 037044b68a6f..e19bd8331e79 100644
--- a/pkgs/by-name/or/orthanc-framework/package.nix
+++ b/pkgs/by-name/or/orthanc-framework/package.nix
@@ -18,10 +18,6 @@ stdenv.mkDerivation (finalAttrs: {
     ;
 
   sourceRoot = "${finalAttrs.src.name}/OrthancFramework/SharedLibrary";
-  outputs = [
-    "out"
-    "dev"
-  ];
 
   buildInputs = orthanc.buildInputs ++ [
     icu
diff --git a/pkgs/by-name/or/orthanc-plugin-dicomweb/fix-orthanc-framework-headers-detection.patch b/pkgs/by-name/or/orthanc-plugin-dicomweb/fix-orthanc-framework-headers-detection.patch
deleted file mode 100644
index 87c92ed94d1b..000000000000
--- a/pkgs/by-name/or/orthanc-plugin-dicomweb/fix-orthanc-framework-headers-detection.patch
+++ /dev/null
@@ -1,16 +0,0 @@
-diff -r ad41d16f36b1 Resources/Orthanc/CMake/DownloadOrthancFramework.cmake
---- a/Resources/Orthanc/CMake/DownloadOrthancFramework.cmake	Fri Jan 17 12:24:54 2025 +0100
-+++ b/Resources/Orthanc/CMake/DownloadOrthancFramework.cmake	Thu Mar 20 17:45:59 2025 +0100
-@@ -552,9 +552,10 @@
-     set(ORTHANC_FRAMEWORK_INCLUDE_DIR ${ORTHANC_FRAMEWORK_ROOT})
-   else()
-     find_path(ORTHANC_FRAMEWORK_INCLUDE_DIR OrthancFramework.h
--      /usr/include/orthanc-framework
--      /usr/local/include/orthanc-framework
-+      /usr/
-+      /usr/local/
-       ${ORTHANC_FRAMEWORK_ROOT}
-+      PATH_SUFFIXES include include/orthanc-framework
-       )
-   endif()
- 
diff --git a/pkgs/by-name/or/orthanc-plugin-dicomweb/package.nix b/pkgs/by-name/or/orthanc-plugin-dicomweb/package.nix
index 160d7bb47949..40e0cdf16ce1 100644
--- a/pkgs/by-name/or/orthanc-plugin-dicomweb/package.nix
+++ b/pkgs/by-name/or/orthanc-plugin-dicomweb/package.nix
@@ -13,7 +13,6 @@
   pugixml,
   libuuid,
   zlib,
-  pkg-config,
 }:
 
 let
@@ -48,11 +47,6 @@ stdenv.mkDerivation (finalAttrs: {
     hash = "sha256-ee271Fcu8yi1gZpTWrCuqhsBdFcPR/JK/fsnJg8PwIc=";
   };
 
-  patches = [
-    # Fix Orthanc Framework headers files detection
-    ./fix-orthanc-framework-headers-detection.patch
-  ];
-
   postPatch = ''
     mkdir -p ThirdPartyDownloads
     ln -s ${bootstrap} ThirdPartyDownloads/bootstrap-5.3.3.zip
@@ -92,6 +86,7 @@ stdenv.mkDerivation (finalAttrs: {
     "-DCMAKE_BUILD_TYPE=Release"
     "-DSTATIC_BUILD=OFF"
     "-DORTHANC_FRAMEWORK_SOURCE=system"
+    "-DORTHANC_FRAMEWORK_ROOT=${orthanc.framework}/include/orthanc-framework"
   ];
 
   meta = {