diff --git a/pkgs/development/libraries/science/math/amd-libflame/default.nix b/pkgs/development/libraries/science/math/amd-libflame/default.nix
index 2ed35d26b907..b03352c54e8a 100644
--- a/pkgs/development/libraries/science/math/amd-libflame/default.nix
+++ b/pkgs/development/libraries/science/math/amd-libflame/default.nix
@@ -9,7 +9,7 @@
 
 , withOpenMP ? true
 , blas64 ? false
-, withAMDOpt ? false
+, withAMDOpt ? true
 }:
 
 stdenv.mkDerivation rec {
@@ -37,15 +37,15 @@ stdenv.mkDerivation rec {
   buildInputs = [ amd-blis aocl-utils ];
 
   cmakeFlags = [
-    "-DLIBAOCLUTILS_LIBRARY_PATH=${lib.getLib aocl-utils}/lib"
+    "-DLIBAOCLUTILS_LIBRARY_PATH=${lib.getLib aocl-utils}/lib/libaoclutils${stdenv.hostPlatform.extensions.sharedLibrary}"
     "-DLIBAOCLUTILS_INCLUDE_PATH=${lib.getDev aocl-utils}/include"
     "-DENABLE_BUILTIN_LAPACK2FLAME=ON"
     "-DENABLE_CBLAS_INTERFACES=ON"
     "-DENABLE_EXT_LAPACK_INTERFACE=ON"
   ]
-  ++ lib.optional (!withOpenMP) "ENABLE_MULTITHREADING=OFF"
-  ++ lib.optional blas64 "ENABLE_ILP64=ON"
-  ++ lib.optional withAMDOpt "ENABLE_AMD_OPT=ON";
+  ++ lib.optional (!withOpenMP) "-DENABLE_MULTITHREADING=OFF"
+  ++ lib.optional blas64 "-DENABLE_ILP64=ON"
+  ++ lib.optional withAMDOpt "-DENABLE_AMD_OPT=ON";
 
   postInstall = ''
     ln -s $out/lib/libflame.so $out/lib/liblapack.so.3