diff --git a/pkgs/by-name/gn/gnome-settings-daemon46/add-gnome-session-ctl-option.patch b/pkgs/by-name/gn/gnome-settings-daemon48/add-gnome-session-ctl-option.patch
similarity index 100%
rename from pkgs/by-name/gn/gnome-settings-daemon46/add-gnome-session-ctl-option.patch
rename to pkgs/by-name/gn/gnome-settings-daemon48/add-gnome-session-ctl-option.patch
diff --git a/pkgs/by-name/gn/gnome-settings-daemon46/fix-paths.patch b/pkgs/by-name/gn/gnome-settings-daemon48/fix-paths.patch
similarity index 100%
rename from pkgs/by-name/gn/gnome-settings-daemon46/fix-paths.patch
rename to pkgs/by-name/gn/gnome-settings-daemon48/fix-paths.patch
diff --git a/pkgs/by-name/gn/gnome-settings-daemon46/package.nix b/pkgs/by-name/gn/gnome-settings-daemon48/package.nix
similarity index 81%
rename from pkgs/by-name/gn/gnome-settings-daemon46/package.nix
rename to pkgs/by-name/gn/gnome-settings-daemon48/package.nix
index 550c7c6d1023..02c1d8ee6940 100644
--- a/pkgs/by-name/gn/gnome-settings-daemon46/package.nix
+++ b/pkgs/by-name/gn/gnome-settings-daemon48/package.nix
@@ -2,6 +2,7 @@
   stdenv,
   lib,
   replaceVars,
+  buildPackages,
   fetchurl,
   meson,
   ninja,
@@ -36,15 +37,17 @@
   tzdata,
   gcr_4,
   gnome-session-ctl,
+  udevCheckHook,
+  withSystemd ? lib.meta.availableOn stdenv.hostPlatform systemd,
 }:
 
 stdenv.mkDerivation (finalAttrs: {
   pname = "gnome-settings-daemon";
-  version = "46.0";
+  version = "48.1";
 
   src = fetchurl {
     url = "mirror://gnome/sources/gnome-settings-daemon/${lib.versions.major finalAttrs.version}/gnome-settings-daemon-${finalAttrs.version}.tar.xz";
-    hash = "sha256-C5oPZPoYqOfgm0yVo/dU+gM8LNvS3DVwHwYYVywcs9c=";
+    hash = "sha256-OGCi6iFNy8tmAK56HjNYpTiSFQh7w+SkfO4/h7ruBi4=";
   };
 
   patches = [
@@ -56,17 +59,24 @@ stdenv.mkDerivation (finalAttrs: {
     })
   ];
 
+  depsBuildBuild = [
+    buildPackages.stdenv.cc
+    pkg-config
+  ];
+
   nativeBuildInputs = [
     meson
     ninja
     pkg-config
     perl
     gettext
+    glib
     libxml2
     libxslt
     docbook_xsl
     wrapGAppsHook3
     python3
+    udevCheckHook
   ];
 
   buildInputs = [
@@ -87,14 +97,19 @@ stdenv.mkDerivation (finalAttrs: {
     polkit
     geocode-glib_2
     geoclue2
-    systemd
     libgudev
     libwacom
     gcr_4
+  ]
+  ++ lib.optionals withSystemd [
+    systemd
   ];
 
   mesonFlags = [
     "-Dudev_dir=${placeholder "out"}/lib/udev"
+    (lib.mesonBool "systemd" withSystemd)
+  ]
+  ++ lib.optionals withSystemd [
     "-Dgnome_session_ctl_path=${gnome-session-ctl}/libexec/gnome-session-ctl"
   ];
 
@@ -103,12 +118,14 @@ stdenv.mkDerivation (finalAttrs: {
   env.NIX_CFLAGS_COMPILE = "-DG_DISABLE_CAST_CHECKS";
 
   postPatch = ''
-    for f in gnome-settings-daemon/codegen.py plugins/power/gsd-power-constants-update.pl; do
+    for f in plugins/power/gsd-power-constants-update.pl; do
       chmod +x $f
       patchShebangs $f
     done
   '';
 
+  doInstallCheck = true;
+
   meta = {
     description = "GNOME Settings Daemon";
     homepage = "https://gitlab.gnome.org/GNOME/gnome-settings-daemon/";
diff --git a/pkgs/desktops/pantheon/default.nix b/pkgs/desktops/pantheon/default.nix
index ce88d24e09d1..aa243007a710 100644
--- a/pkgs/desktops/pantheon/default.nix
+++ b/pkgs/desktops/pantheon/default.nix
@@ -47,8 +47,8 @@ lib.makeScope pkgs.newScope (
 
     mutter = pkgs.mutter48;
 
-    # Using 43 to match Mutter used in Pantheon
-    gnome-settings-daemon = pkgs.gnome-settings-daemon46;
+    # Using 48 to match Mutter used in Pantheon
+    gnome-settings-daemon = pkgs.gnome-settings-daemon48;
 
     elementary-gsettings-schemas = callPackage ./desktop/elementary-gsettings-schemas { };
 
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 1f1ae3d2d466..7189c4978b2e 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -778,6 +778,7 @@ mapAliases {
   gnome-passwordsafe = throw "'gnome-passwordsafe' has been renamed to/replaced by 'gnome-secrets'"; # Converted to throw 2025-10-27
   gnome-recipes = throw "'gnome-recipes' has been removed due to lack of upstream maintenance and dependency on insecure libraries"; # Added 2025-09-06
   gnome-resources = throw "'gnome-resources' has been renamed to/replaced by 'resources'"; # Converted to throw 2025-10-27
+  gnome-settings-daemon46 = throw "'gnome-settings-daemon46' has been removed, no longer used by Pantheon"; # Added 2026-01-24
   gns3Packages = throw "'gns3Packages' has been removed. Use 'gns3-gui' and 'gns3-server' instead."; # Added 2026-01-18
   gnu-cobol = throw "'gnu-cobol' has been renamed to/replaced by 'gnucobol'"; # Converted to throw 2025-10-27
   gnubik = throw "'gnubik' has been removed due to lack of maintenance upstream and its dependency on GTK 2"; # Added 2025-09-16