diff --git a/pkgs/development/python-modules/protobuf/default.nix b/pkgs/development/python-modules/protobuf/default.nix
index d0f8e3bba99d..2676dc90d68b 100644
--- a/pkgs/development/python-modules/protobuf/default.nix
+++ b/pkgs/development/python-modules/protobuf/default.nix
@@ -33,6 +33,14 @@ buildPythonPackage {
       src = ./use-nixpkgs-abseil-cpp.patch;
       abseil_cpp_include_path = "${lib.getDev protobuf.abseil-cpp}/include";
     })
+  ]
+  ++ lib.optionals (pythonAtLeast "3.11" && lib.versionOlder protobuf.version "3.22") [
+    (fetchpatch {
+      name = "support-python311.patch";
+      url = "https://github.com/protocolbuffers/protobuf/commit/2206b63c4649cf2e8a06b66c9191c8ef862ca519.diff";
+      stripLen = 1; # because sourceRoot above
+      hash = "sha256-3GaoEyZIhS3QONq8LEvJCH5TdO9PKnOgcQF0GlEiwFo=";
+    })
   ];
 
   prePatch = ''