diff --git a/pkgs/applications/misc/cura/stable.nix b/pkgs/applications/misc/cura/stable.nix
deleted file mode 100644
index d330a8a5ae28..000000000000
--- a/pkgs/applications/misc/cura/stable.nix
+++ /dev/null
@@ -1,72 +0,0 @@
-{ lib, stdenv, python27Packages, curaengine, makeDesktopItem, fetchFromGitHub }:
-
-stdenv.mkDerivation rec {
-  pname = "cura";
-  version = "15.06.03";
-
-  src = fetchFromGitHub {
-    owner = "daid";
-    repo = "Cura";
-    rev = version;
-    sha256 = "sha256-o1cAi4Wi19WOijlRB9iYwNEpSNnmywUj5Bth8rRhqFA=";
-  };
-
-  desktopItem = makeDesktopItem {
-    name = "Cura";
-    exec = "cura";
-    icon = "cura";
-    comment = "Cura";
-    desktopName = "Cura";
-    genericName = "3D printing host software";
-    categories = [ "GNOME" "GTK" "Utility" ];
-  };
-
-  python_deps = with python27Packages; [ pyopengl pyserial numpy wxPython30 power setuptools ];
-
-  pythonPath = python_deps;
-
-  propagatedBuildInputs = python_deps;
-
-  buildInputs = [ curaengine python27Packages.wrapPython ];
-
-  configurePhase = "";
-  buildPhase = "";
-
-  patches = [ ./numpy-cast.patch ];
-
-  installPhase = ''
-    # Install Python code.
-    site_packages=$out/lib/python2.7/site-packages
-    mkdir -p $site_packages
-    cp -r Cura $site_packages/
-
-    # Install resources.
-    resources=$out/share/cura
-    mkdir -p $resources
-    cp -r resources/* $resources/
-    sed -i 's|os.path.join(os.path.dirname(__file__), "../../resources")|"'$resources'"|g' $site_packages/Cura/util/resources.py
-
-    # Install executable.
-    mkdir -p $out/bin
-    cp Cura/cura.py $out/bin/cura
-    chmod +x $out/bin/cura
-    sed -i 's|#!/usr/bin/python|#!/usr/bin/env python|' $out/bin/cura
-    wrapPythonPrograms
-
-    # Make it find CuraEngine.
-    echo "def getEngineFilename(): return '${curaengine}/bin/CuraEngine'" >> $site_packages/Cura/util/sliceEngine.py
-
-    # Install desktop item.
-    mkdir -p "$out"/share/applications
-    cp "$desktopItem"/share/applications/* "$out"/share/applications/
-    mkdir -p "$out"/share/icons
-    ln -s "$resources/images/c.png" "$out"/share/icons/cura.png
-  '';
-
-  meta = with lib; {
-    description = "3D printing host software";
-    homepage = "https://github.com/daid/Cura";
-    license = licenses.agpl3;
-    platforms = platforms.linux;
-  };
-}
diff --git a/pkgs/applications/misc/haxor-news/default.nix b/pkgs/applications/misc/haxor-news/default.nix
index c93d31f66305..9170af04e61c 100644
--- a/pkgs/applications/misc/haxor-news/default.nix
+++ b/pkgs/applications/misc/haxor-news/default.nix
@@ -16,7 +16,13 @@ let
         };
       });
       # Use click 7
-      click = self.callPackage ../../../development/python2-modules/click/default.nix { };
+      click = super.click.overridePythonAttrs (old: rec {
+        version = "7.1.2";
+        src = old.src.override {
+          inherit version;
+          sha256 = "d2b5255c7c6349bc1bd1e59e08cd12acbbd63ce649f2588755783aa94dfb6b1a";
+        };
+      });
     };
   };
 in
diff --git a/pkgs/applications/misc/plover/default.nix b/pkgs/applications/misc/plover/default.nix
index 02162a4039e3..6bd4ee6b3c18 100644
--- a/pkgs/applications/misc/plover/default.nix
+++ b/pkgs/applications/misc/plover/default.nix
@@ -2,30 +2,7 @@
   qtbase, mkDerivationWith }:
 
 {
-  stable = with python27Packages; buildPythonPackage rec {
-    pname = "plover";
-    version = "3.1.1";
-
-    meta = with lib; {
-      broken = stdenv.isDarwin;
-      description = "OpenSteno Plover stenography software";
-      maintainers = with maintainers; [ twey kovirobi ];
-      license     = licenses.gpl2;
-    };
-
-    src = fetchFromGitHub {
-      owner = "openstenoproject";
-      repo = "plover";
-      rev = "v${version}";
-      sha256 = "sha256-LIhTwHMphg+xTR9NKvjAZ6p0mmqPNcZd9C4cgnenmYQ=";
-    };
-
-    nativeBuildInputs     = [ setuptools-scm ];
-    buildInputs           = [ pytest mock ];
-    propagatedBuildInputs = [
-      six setuptools pyserial appdirs hidapi wxPython xlib wmctrl dbus-python
-    ];
-  };
+  stable = throw "plover.stable was removed because it used Python 2. Use plover.dev instead."; # added 2022-06-05
 
   dev = with python3Packages; mkDerivationWith buildPythonPackage rec {
     pname = "plover";
diff --git a/pkgs/applications/misc/privacyidea/default.nix b/pkgs/applications/misc/privacyidea/default.nix
index d89364280795..5c3afc301556 100644
--- a/pkgs/applications/misc/privacyidea/default.nix
+++ b/pkgs/applications/misc/privacyidea/default.nix
@@ -65,18 +65,30 @@ let
           sha256 = "sha256-WUxngH+xYjizDES99082wCzfItHIzake+KDtjav1Ygo=";
         };
       });
-      # Required by flask-babel
       itsdangerous = super.itsdangerous.overridePythonAttrs (old: rec {
-        version = "2.0.1";
+        version = "1.1.0";
         src = old.src.override {
           inherit version;
-          sha256 = "sha256-nnJNaPwikCoUNTUfhMP7hiPzA//8xWaky5Ut+MVyz/A=";
+          sha256 = "321b033d07f2a4136d3ec762eac9f16a10ccd60f53c0c91af90217ace7ba1f19";
+        };
+      });
+      flask = super.flask.overridePythonAttrs (old: rec {
+        version = "1.1.4";
+        src = old.src.override {
+          inherit version;
+          sha256 = "0fbeb6180d383a9186d0d6ed954e0042ad9f18e0e8de088b2b419d526927d196";
         };
       });
-      flask = self.callPackage ../../../development/python2-modules/flask { };
       sqlsoup = super.sqlsoup.overrideAttrs ({ meta ? {}, ... }: {
         meta = meta // { broken = false; };
       });
+      click = super.click.overridePythonAttrs (old: rec {
+        version = "7.1.2";
+        src = old.src.override {
+          inherit version;
+          sha256 = "d2b5255c7c6349bc1bd1e59e08cd12acbbd63ce649f2588755783aa94dfb6b1a";
+        };
+      });
     };
   };
 in
diff --git a/pkgs/applications/networking/instant-messengers/salut-a-toi/default.nix b/pkgs/applications/networking/instant-messengers/salut-a-toi/default.nix
deleted file mode 100644
index 6a6302e74955..000000000000
--- a/pkgs/applications/networking/instant-messengers/salut-a-toi/default.nix
+++ /dev/null
@@ -1,60 +0,0 @@
-{ lib, stdenv, fetchurl, python27Packages, file }:
-
-let
-  inherit (python27Packages) python;
-  requirements = (import ./requirements.nix {
-    inherit lib fetchurl;
-    pythonPackages = python27Packages;
-  });
-
-in
-  stdenv.mkDerivation rec {
-    pname = "salut-a-toi";
-    version = "0.6.1";
-
-    src = fetchurl {
-      url = "ftp://ftp.goffi.org/sat/sat-${version}.tar.bz2";
-      sha256 = "0kn9403n8fpzl0hsb9kkzicsmzq2fjl627l31yykbqzc4nsr780d";
-    };
-
-    buildInputs = with python27Packages;
-    [
-      python twisted urwid wxPython pygobject2
-      dbus-python wrapPython setuptools file
-      pycrypto pyxdg
-    ] ++  (with requirements; [
-      pyfeed
-      wokkel
-    ]);
-
-    configurePhase = ''
-      sed -i "/use_setuptools/d" setup.py
-      sed -e "s@sys.prefix@'$out'@g" -i setup.py
-      sed -e "1aexport PATH=\"\$PATH\":\"$out/bin\":\"${python27Packages.twisted}/bin\"" -i src/sat.sh
-      sed -e "1aexport PYTHONPATH=\"\$PYTHONPATHPATH\":\"$PYTHONPATH\":"$out/${python.sitePackages}"" -i src/sat.sh
-
-      echo 'import wokkel.muc' | python
-    '';
-
-    buildPhase = ''
-      ${python.interpreter} setup.py build
-    '';
-
-    installPhase = ''
-      ${python.interpreter} setup.py install --prefix="$out"
-
-      for i in "$out/bin"/*; do
-      head -n 1 "$i" | grep -E '[/ ]python( |$)' && {
-        wrapProgram "$i" --prefix PYTHONPATH : "$PYTHONPATH:$out/${python.sitePackages}"
-      } || true
-      done
-    '';
-
-    meta = with lib; {
-      homepage = "http://sat.goffi.org/";
-      description = "A multi-frontend XMPP client";
-      platforms = platforms.linux;
-      maintainers = [ maintainers.raskin ];
-      license = licenses.gpl3Plus;
-    };
-  }
diff --git a/pkgs/applications/networking/instant-messengers/salut-a-toi/requirements.nix b/pkgs/applications/networking/instant-messengers/salut-a-toi/requirements.nix
deleted file mode 100644
index a8e711c447d5..000000000000
--- a/pkgs/applications/networking/instant-messengers/salut-a-toi/requirements.nix
+++ /dev/null
@@ -1,67 +0,0 @@
-{ fetchurl
-, lib
-, pythonPackages
-}:
-
-let
-  buildPythonPackage = pythonPackages.buildPythonPackage;
-
-  xe = buildPythonPackage rec {
-    url = "http://www.blarg.net/%7Esteveha/xe-0.7.4.tar.gz";
-    name = lib.nameFromURL url ".tar";
-    src = fetchurl {
-      inherit url;
-      sha256 = "0v9878cl0y9cczdsr6xjy8v9l139lc23h4m5f86p4kpf2wlnpi42";
-    };
-
-    # error: invalid command 'test'
-    doCheck = false;
-
-    meta = {
-      homepage = "http://home.blarg.net/~steveha/xe.html";
-      description = "XML elements";
-    };
-  };
-
-in {
-
-  pyfeed = (buildPythonPackage rec {
-    url = "http://www.blarg.net/%7Esteveha/pyfeed-0.7.4.tar.gz";
-
-    name = lib.nameFromURL url ".tar";
-
-    src = fetchurl {
-      inherit url;
-      sha256 = "1h4msq573m7wm46h3cqlx4rsn99f0l11rhdqgf50lv17j8a8vvy1";
-    };
-
-    propagatedBuildInputs = [ xe ];
-
-    # error: invalid command 'test'
-    doCheck = false;
-
-    meta = with lib; {
-      homepage = "http://home.blarg.net/~steveha/pyfeed.html";
-      description = "Tools for syndication feeds";
-    };
-
-  });
-
-  wokkel = buildPythonPackage (rec {
-    url = "http://wokkel.ik.nu/releases/0.7.0/wokkel-0.7.0.tar.gz";
-    name = lib.nameFromURL url ".tar";
-    src = fetchurl {
-      inherit url;
-      sha256 = "0rnshrzw8605x05mpd8ndrx3ri8h6cx713mp8sl4f04f4gcrz8ml";
-    };
-
-    propagatedBuildInputs = with pythonPackages; [twisted python-dateutil];
-
-    meta = with lib; {
-      description = "Some (mainly XMPP-related) additions to twisted";
-      homepage = "http://wokkel.ik.nu/";
-      license = licenses.mit;
-    };
-  });
-
-}
diff --git a/pkgs/applications/networking/instant-messengers/torchat/default.nix b/pkgs/applications/networking/instant-messengers/torchat/default.nix
deleted file mode 100644
index 224a70ce9f72..000000000000
--- a/pkgs/applications/networking/instant-messengers/torchat/default.nix
+++ /dev/null
@@ -1,40 +0,0 @@
-{ lib, stdenv, fetchFromGitHub, python2, unzip, tor }:
-
-stdenv.mkDerivation rec {
-  pname = "torchat";
-  version = "0.9.9.553";
-
-  src = fetchFromGitHub {
-    owner = "prof7bit";
-    repo = "TorChat";
-    rev = version;
-    sha256 = "2LHG9qxZDo5rV6wsputdRo2Y1aHs+irMwt1ucFnXQE0=";
-  };
-
-  nativeBuildInputs = [ unzip ];
-  buildInputs = with python2.pkgs; [ python wxPython wrapPython ];
-  pythonPath = with python2.pkgs; [ wxPython ];
-
-  preConfigure = "cd torchat/src; rm portable.txt";
-
-  installPhase = ''
-    substituteInPlace "Tor/tor.sh" --replace "tor -f" "${tor}/bin/tor -f"
-
-    wrapPythonPrograms
-
-    mkdir -p $out/lib/torchat
-    cp -rf * $out/lib/torchat
-    makeWrapper ${python2}/bin/python $out/bin/torchat \
-        --set PYTHONPATH $out/lib/torchat:$program_PYTHONPATH \
-        --chdir "$out/lib/torchat" \
-        --add-flags "-O $out/lib/torchat/torchat.py"
-  '';
-
-  meta = with lib; {
-    homepage = "https://github.com/prof7bit/TorChat";
-    description = "Instant messaging application on top of the Tor network and it's location hidden services";
-    license = licenses.gpl3;
-    maintainers = [ ];
-    platforms = platforms.unix;
-  };
-}
diff --git a/pkgs/development/python2-modules/click/default.nix b/pkgs/development/python2-modules/click/default.nix
deleted file mode 100644
index fcbd4d0981af..000000000000
--- a/pkgs/development/python2-modules/click/default.nix
+++ /dev/null
@@ -1,28 +0,0 @@
-{ lib, buildPythonPackage, fetchPypi, locale, pytestCheckHook }:
-
-buildPythonPackage rec {
-  pname = "click";
-  version = "7.1.2";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "d2b5255c7c6349bc1bd1e59e08cd12acbbd63ce649f2588755783aa94dfb6b1a";
-  };
-
-  postPatch = ''
-    substituteInPlace src/click/_unicodefun.py \
-      --replace "'locale'" "'${locale}/bin/locale'"
-  '';
-
-  checkInputs = [ pytestCheckHook ];
-
-  meta = with lib; {
-    homepage = "https://click.palletsprojects.com/";
-    description = "Create beautiful command line interfaces in Python";
-    longDescription = ''
-      A Python package for creating beautiful command line interfaces in a
-      composable way, with as little code as necessary.
-    '';
-    license = licenses.bsd3;
-  };
-}
diff --git a/pkgs/development/python2-modules/cryptography/default.nix b/pkgs/development/python2-modules/cryptography/default.nix
deleted file mode 100644
index 0b4e2ae394cd..000000000000
--- a/pkgs/development/python2-modules/cryptography/default.nix
+++ /dev/null
@@ -1,86 +0,0 @@
-{ lib
-, stdenv
-, callPackage
-, buildPythonPackage
-, fetchPypi
-, isPy27
-, ipaddress
-, openssl
-, darwin
-, packaging
-, six
-, isPyPy
-, cffi
-, pytest
-, pretend
-, iso8601
-, pytz
-, hypothesis
-, enum34
-}:
-
-let
-  cryptography-vectors = callPackage ./vectors.nix { };
-in
-buildPythonPackage rec {
-  pname = "cryptography";
-  version = "3.3.2"; # Also update the hash in vectors-3.3.nix
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "1vcvw4lkw1spiq322pm1256kail8nck6bbgpdxx3pqa905wd6q2s";
-  };
-
-  patches = [ ./cryptography-py27-warning.patch ];
-
-  outputs = [ "out" "dev" ];
-
-  nativeBuildInputs = lib.optionals (!isPyPy) [
-    cffi
-  ];
-
-  buildInputs = [ openssl ]
-    ++ lib.optional stdenv.isDarwin darwin.apple_sdk.frameworks.Security;
-  propagatedBuildInputs = [
-    packaging
-    six
-  ] ++ lib.optionals (!isPyPy) [
-    cffi
-  ] ++ lib.optionals isPy27 [
-    ipaddress
-    enum34
-  ];
-
-  checkInputs = [
-    cryptography-vectors
-    hypothesis
-    iso8601
-    pretend
-    pytest
-    pytz
-  ];
-
-  checkPhase = ''
-    py.test --disable-pytest-warnings tests
-  '';
-
-  # IOKit's dependencies are inconsistent between OSX versions, so this is the best we
-  # can do until nix 1.11's release
-  __impureHostDeps = [ "/usr/lib" ];
-
-  meta = with lib; {
-    description = "A package which provides cryptographic recipes and primitives";
-    longDescription = ''
-      Cryptography includes both high level recipes and low level interfaces to
-      common cryptographic algorithms such as symmetric ciphers, message
-      digests, and key derivation functions.
-      Our goal is for it to be your "cryptographic standard library". It
-      supports Python 2.7, Python 3.5+, and PyPy 5.4+.
-    '';
-    homepage = "https://github.com/pyca/cryptography";
-    changelog = "https://cryptography.io/en/latest/changelog/#v"
-      + replaceStrings [ "." ] [ "-" ] version;
-    license = with licenses; [ asl20 bsd3 psfl ];
-    maintainers = with maintainers; [ primeos ];
-  };
-}
diff --git a/pkgs/development/python2-modules/cryptography/vectors.nix b/pkgs/development/python2-modules/cryptography/vectors.nix
deleted file mode 100644
index 4d6214807e73..000000000000
--- a/pkgs/development/python2-modules/cryptography/vectors.nix
+++ /dev/null
@@ -1,24 +0,0 @@
-{ buildPythonPackage, fetchPypi, lib, cryptography }:
-
-buildPythonPackage rec {
-  pname = "cryptography-vectors";
-  # The test vectors must have the same version as the cryptography package:
-  version = cryptography.version;
-
-  src = fetchPypi {
-    pname = "cryptography_vectors";
-    inherit version;
-    sha256 = "1yhaps0f3h2yjb6lmz953z1l1d84y9swk4k3gj9nqyk4vbx5m7cc";
-  };
-
-  # No tests included
-  doCheck = false;
-
-  meta = with lib; {
-    description = "Test vectors for the cryptography package";
-    homepage = "https://cryptography.io/en/latest/development/test-vectors/";
-    # Source: https://github.com/pyca/cryptography/tree/master/vectors;
-    license = with licenses; [ asl20 bsd3 ];
-    maintainers = with maintainers; [ primeos ];
-  };
-}
diff --git a/pkgs/development/python2-modules/decorator/default.nix b/pkgs/development/python2-modules/decorator/default.nix
deleted file mode 100644
index 8e8fd28f0b54..000000000000
--- a/pkgs/development/python2-modules/decorator/default.nix
+++ /dev/null
@@ -1,21 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-}:
-
-buildPythonPackage rec {
-  pname = "decorator";
-  version = "4.4.2";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "1rxzhk5zwiggk45hl53zydvy70lk654kg0nc1p54090p402jz9p3";
-  };
-
-  meta = with lib; {
-    homepage = "https://pypi.python.org/pypi/decorator";
-    description = "Better living through Python with decorators";
-    license = lib.licenses.mit;
-    maintainers = [ maintainers.costrouc ];
-  };
-}
diff --git a/pkgs/development/python2-modules/flask/default.nix b/pkgs/development/python2-modules/flask/default.nix
deleted file mode 100644
index 27f436c3c53c..000000000000
--- a/pkgs/development/python2-modules/flask/default.nix
+++ /dev/null
@@ -1,28 +0,0 @@
-{ lib, buildPythonPackage, fetchPypi
-, itsdangerous, click, werkzeug, jinja2, pytest }:
-
-buildPythonPackage rec {
-  version = "1.1.2";
-  pname = "Flask";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "4efa1ae2d7c9865af48986de8aeb8504bf32c7f3d6fdc9353d34b21f4b127060";
-  };
-
-  checkInputs = [ pytest ];
-  propagatedBuildInputs = [ itsdangerous click werkzeug jinja2 ];
-
-  checkPhase = ''
-    py.test
-  '';
-
-  # Tests require extra dependencies
-  doCheck = false;
-
-  meta = with lib; {
-    homepage = "http://flask.pocoo.org/";
-    description = "A microframework based on Werkzeug, Jinja 2, and good intentions";
-    license = licenses.bsd3;
-  };
-}
diff --git a/pkgs/development/python2-modules/freezegun/default.nix b/pkgs/development/python2-modules/freezegun/default.nix
deleted file mode 100644
index 7f77616f2a4e..000000000000
--- a/pkgs/development/python2-modules/freezegun/default.nix
+++ /dev/null
@@ -1,29 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-, python-dateutil
-, six
-, mock
-, nose
-, pytest
-}:
-
-buildPythonPackage rec {
-  pname = "freezegun";
-  version = "0.3.15";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "e2062f2c7f95cc276a834c22f1a17179467176b624cc6f936e8bc3be5535ad1b";
-  };
-
-  propagatedBuildInputs = [ python-dateutil six ];
-  checkInputs = [ mock nose pytest ];
-
-  meta = with lib; {
-    description = "FreezeGun: Let your Python tests travel through time";
-    homepage = "https://github.com/spulec/freezegun";
-    license = licenses.asl20;
-  };
-
-}
diff --git a/pkgs/development/python2-modules/ipaddr/default.nix b/pkgs/development/python2-modules/ipaddr/default.nix
deleted file mode 100644
index b29ee9179287..000000000000
--- a/pkgs/development/python2-modules/ipaddr/default.nix
+++ /dev/null
@@ -1,23 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-, isPy3k
-}:
-
-buildPythonPackage rec {
-  pname = "ipaddr";
-  version = "2.2.0";
-  disabled = isPy3k;
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "1ml8r8z3f0mnn381qs1snbffa920i9ycp6mm2am1d3aqczkdz4j0";
-  };
-
-  meta = with lib; {
-    description = "Google's IP address manipulation library";
-    homepage = "https://github.com/google/ipaddr-py";
-    license = licenses.asl20;
-  };
-
-}
diff --git a/pkgs/development/python2-modules/itsdangerous/default.nix b/pkgs/development/python2-modules/itsdangerous/default.nix
deleted file mode 100644
index d1669a1ed5bf..000000000000
--- a/pkgs/development/python2-modules/itsdangerous/default.nix
+++ /dev/null
@@ -1,21 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-}:
-
-buildPythonPackage rec {
-  pname = "itsdangerous";
-  version = "1.1.0";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "321b033d07f2a4136d3ec762eac9f16a10ccd60f53c0c91af90217ace7ba1f19";
-  };
-
-  meta = with lib; {
-    description = "Helpers to pass trusted data to untrusted environments and back";
-    homepage = "https://pypi.python.org/pypi/itsdangerous/";
-    license = licenses.bsd0;
-  };
-
-}
diff --git a/pkgs/development/python2-modules/libcloud/default.nix b/pkgs/development/python2-modules/libcloud/default.nix
deleted file mode 100644
index 504e7753a978..000000000000
--- a/pkgs/development/python2-modules/libcloud/default.nix
+++ /dev/null
@@ -1,39 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-, isPy27
-, mock
-, pycrypto
-, requests
-, pytest-runner
-, pytest
-, requests-mock
-, typing
-, backports_ssl_match_hostname
-}:
-
-buildPythonPackage rec {
-  pname = "apache-libcloud";
-  version = "2.8.3";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "70096690b24a7832cc5abdfda1954b49fddc1c09a348a1e6caa781ac867ed4c6";
-  };
-
-  checkInputs = [ mock pytest pytest-runner requests-mock ];
-  propagatedBuildInputs = [ pycrypto requests ]
-    ++ lib.optionals isPy27 [ typing backports_ssl_match_hostname ];
-
-  preConfigure = "cp libcloud/test/secrets.py-dist libcloud/test/secrets.py";
-
-  # requires a certificates file
-  doCheck = false;
-
-  meta = with lib; {
-    description = "A unified interface to many cloud providers";
-    homepage = "https://libcloud.apache.org/";
-    license = licenses.asl20;
-  };
-
-}
diff --git a/pkgs/development/python2-modules/lpod/default.nix b/pkgs/development/python2-modules/lpod/default.nix
deleted file mode 100644
index 9c719d234f89..000000000000
--- a/pkgs/development/python2-modules/lpod/default.nix
+++ /dev/null
@@ -1,31 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchFromGitHub
-, lxml
-, docutils
-, pillow
-, isPy3k
-}:
-
-buildPythonPackage {
-  version = "1.1.7";
-  pname = "python-lpod";
-  # lpod library currently does not support Python 3.x
-  disabled = isPy3k;
-
-  propagatedBuildInputs = [ lxml docutils pillow ];
-
-  src = fetchFromGitHub {
-    owner = "lpod";
-    repo = "lpod-python";
-    rev = "dee32120ee582ff337b0c52a95a9a87cca71fd67";
-    sha256 = "1mikvzp27wxkzpr2lii4wg1hhx8h610agckqynvsrdc8v3nw9ciw";
-  };
-
-  meta = with lib; {
-    homepage = "https://github.com/lpod/lpod-python/";
-    description = "Library implementing the ISO/IEC 26300 OpenDocument Format standard (ODF) ";
-    license = licenses.gpl3;
-  };
-
-}
diff --git a/pkgs/development/python2-modules/pyjwt/default.nix b/pkgs/development/python2-modules/pyjwt/default.nix
deleted file mode 100644
index 011f526e520f..000000000000
--- a/pkgs/development/python2-modules/pyjwt/default.nix
+++ /dev/null
@@ -1,47 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-, cryptography
-, ecdsa
-, pytestCheckHook
-, pythonOlder
-}:
-
-buildPythonPackage rec {
-  pname = "pyjwt";
-  version = "1.7.1";
-
-  src = fetchPypi {
-    pname = "PyJWT";
-    inherit version;
-    sha256 = "8d59a976fb773f3e6a39c85636357c4f0e242707394cadadd9814f5cbaa20e96";
-  };
-
-  postPatch = ''
-    sed -i '/^addopts/d' setup.cfg
-  '';
-
-  propagatedBuildInputs = [
-    cryptography
-    ecdsa
-  ];
-
-  checkInputs = [
-    pytestCheckHook
-  ];
-
-  disabledTests = [
-    "test_ec_verify_should_return_false_if_signature_invalid"
-  ];
-
-  pythonImportsCheck = [ "jwt" ];
-
-  meta = with lib; {
-    description = "JSON Web Token implementation in Python";
-    homepage = "https://github.com/jpadilla/pyjwt";
-    license = licenses.mit;
-    knownVulnerabilities = [
-      "CVE-2022-29217"
-    ];
-  };
-}
diff --git a/pkgs/development/python2-modules/urllib3/default.nix b/pkgs/development/python2-modules/urllib3/default.nix
deleted file mode 100644
index c23835ce4dc2..000000000000
--- a/pkgs/development/python2-modules/urllib3/default.nix
+++ /dev/null
@@ -1,84 +0,0 @@
-{ lib
-, brotli
-, buildPythonPackage
-, certifi
-, cryptography
-, python-dateutil
-, fetchpatch
-, fetchPypi
-, idna
-, mock
-, pyopenssl
-, pysocks
-, pytest-freezegun
-, pytest-timeout
-, pytestCheckHook
-, tornado
-, trustme
-}:
-
-buildPythonPackage rec {
-  pname = "urllib3";
-  version = "1.26.2";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "19188f96923873c92ccb987120ec4acaa12f0461fa9ce5d3d0772bc965a39e08";
-  };
-
-  patches = [
-    (fetchpatch {
-      name = "CVE-2021-28363.patch";
-      url = "https://github.com/urllib3/urllib3/commit/8d65ea1ecf6e2cdc27d42124e587c1b83a3118b0.patch";
-      sha256 = "1lqhrd11p03iv14bp89rh67ynf000swmwsfvr3jpfdycdqr3ka9q";
-    })
-  ];
-
-  propagatedBuildInputs = [
-    brotli
-    certifi
-    cryptography
-    idna
-    pyopenssl
-    pysocks
-  ];
-
-  checkInputs = [
-    python-dateutil
-    mock
-    pytest-freezegun
-    pytest-timeout
-    pytestCheckHook
-    tornado
-    trustme
-  ];
-
-  # Tests in urllib3 are mostly timeout-based instead of event-based and
-  # are therefore inherently flaky. On your own machine, the tests will
-  # typically build fine, but on a loaded cluster such as Hydra random
-  # timeouts will occur.
-  #
-  # The urllib3 test suite has two different timeouts in their test suite
-  # (see `test/__init__.py`):
-  # - SHORT_TIMEOUT
-  # - LONG_TIMEOUT
-  # When CI is in the env, LONG_TIMEOUT will be significantly increased.
-  # Still, failures can occur and for that reason tests are disabled.
-  doCheck = false;
-
-  preCheck = ''
-    export CI # Increases LONG_TIMEOUT
-  '';
-
-  pythonImportsCheck = [ "urllib3" ];
-
-  meta = with lib; {
-    description = "Powerful, sanity-friendly HTTP client for Python";
-    homepage = "https://github.com/shazow/urllib3";
-    license = licenses.mit;
-    maintainers = with maintainers; [ fab ];
-    knownVulnerabilities = [
-      "CVE-2021-33503"
-    ];
-  };
-}
diff --git a/pkgs/development/python2-modules/vcrpy/default.nix b/pkgs/development/python2-modules/vcrpy/default.nix
deleted file mode 100644
index ddd4015aad1e..000000000000
--- a/pkgs/development/python2-modules/vcrpy/default.nix
+++ /dev/null
@@ -1,48 +0,0 @@
-{ buildPythonPackage
-, lib
-, six
-, fetchPypi
-, pyyaml
-, mock
-, contextlib2
-, wrapt
-, pytest
-, pytest-httpbin
-, yarl
-, pythonOlder
-, pythonAtLeast
-}:
-
-buildPythonPackage rec {
-  pname = "vcrpy";
-  version = "3.0.0";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "21168d5ae14263a833d4b71acfd8278d8841114f24be1b4ab4a5719d0c7f07bc";
-  };
-
-  checkInputs = [
-    pytest
-    pytest-httpbin
-  ];
-
-  propagatedBuildInputs = [
-    pyyaml
-    wrapt
-    six
-  ]
-  ++ lib.optionals (pythonOlder "3.3") [ contextlib2 mock ]
-  ++ lib.optionals (pythonAtLeast "3.4") [ yarl ];
-
-  checkPhase = ''
-    py.test --ignore=tests/integration -k "not TestVCRConnection"
-  '';
-
-  meta = with lib; {
-    description = "Automatically mock your HTTP interactions to simplify and speed up testing";
-    homepage = "https://github.com/kevin1024/vcrpy";
-    license = licenses.mit;
-  };
-}
-
diff --git a/pkgs/development/python2-modules/werkzeug/default.nix b/pkgs/development/python2-modules/werkzeug/default.nix
deleted file mode 100644
index c03cc6935d2f..000000000000
--- a/pkgs/development/python2-modules/werkzeug/default.nix
+++ /dev/null
@@ -1,60 +0,0 @@
-{ lib, stdenv, buildPythonPackage, fetchPypi
-, itsdangerous, hypothesis
-, pytestCheckHook, requests
-, pytest-timeout
- }:
-
-buildPythonPackage rec {
-  pname = "Werkzeug";
-  version = "1.0.1";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "6c80b1e5ad3665290ea39320b91e1be1e0d5f60652b964a3070216de83d2e47c";
-  };
-
-  propagatedBuildInputs = [ itsdangerous ];
-  checkInputs = [ pytestCheckHook requests hypothesis pytest-timeout ];
-
-  postPatch = ''
-    # ResourceWarning causes tests to fail
-    rm tests/test_routing.py
-  '';
-
-  disabledTests = [
-    "test_save_to_pathlib_dst"
-    "test_cookie_maxsize"
-    "test_cookie_samesite_attribute"
-    "test_cookie_samesite_invalid"
-    "test_range_parsing"
-    "test_content_range_parsing"
-    "test_http_date_lt_1000"
-    "test_best_match_works"
-    "test_date_to_unix"
-    "test_easteregg"
-
-    # Seems to be a problematic test-case:
-    #
-    # > warnings.warn(pytest.PytestUnraisableExceptionWarning(msg))
-    # E pytest.PytestUnraisableExceptionWarning: Exception ignored in: <_io.FileIO [closed]>
-    # E
-    # E Traceback (most recent call last):
-    # E   File "/nix/store/cwv8aj4vsqvimzljw5dxsxy663vjgibj-python3.9-Werkzeug-1.0.1/lib/python3.9/site-packages/werkzeug/formparser.py", line 318, in parse_multipart_headers
-    # E     return Headers(result)
-    # E ResourceWarning: unclosed file <_io.FileIO name=11 mode='rb+' closefd=True>
-    "test_basic_routing"
-    "test_merge_slashes_match"
-    "test_merge_slashes_build"
-    "TestMultiPart"
-    "TestHTTPUtility"
-  ] ++ lib.optionals stdenv.isDarwin [
-    "test_get_machine_id"
-  ];
-
-  meta = with lib; {
-    homepage = "https://palletsprojects.com/p/werkzeug/";
-    description = "A WSGI utility library for Python";
-    license = licenses.bsd3;
-    maintainers = [ ];
-  };
-}
diff --git a/pkgs/development/python2-modules/wsproto/default.nix b/pkgs/development/python2-modules/wsproto/default.nix
deleted file mode 100644
index a8488d8c4ab8..000000000000
--- a/pkgs/development/python2-modules/wsproto/default.nix
+++ /dev/null
@@ -1,25 +0,0 @@
-{ lib, buildPythonPackage, fetchPypi, h11, enum34, pytest }:
-
-buildPythonPackage rec {
-  pname = "wsproto";
-  version = "0.14.1";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "051s127qb5dladxa14n9nqajwq7xki1dz1was5r5v9df5a0jq8pd";
-  };
-
-  propagatedBuildInputs = [ h11 enum34 ];
-
-  checkInputs = [ pytest ];
-
-  checkPhase = ''
-    py.test
-  '';
-
-  meta = with lib; {
-    description = "Pure Python, pure state-machine WebSocket implementation";
-    homepage = "https://github.com/python-hyper/wsproto/";
-    license = licenses.mit;
-  };
-}
diff --git a/pkgs/development/python2-modules/wxPython/default.nix b/pkgs/development/python2-modules/wxPython/default.nix
deleted file mode 100644
index 6649c5f69315..000000000000
--- a/pkgs/development/python2-modules/wxPython/default.nix
+++ /dev/null
@@ -1,91 +0,0 @@
-{ fetchurl
-, lib
-, stdenv
-, darwin
-, openglSupport ? true
-, libX11
-, wxGTK
-, wxmac
-, pkg-config
-, buildPythonPackage
-, pyopengl
-, isPy3k
-, isPyPy
-, python
-, cairo
-, pango
-}:
-
-assert wxGTK.unicode;
-
-buildPythonPackage rec {
-  pname = "wxPython";
-  version = "3.0.2.0";
-
-  disabled = isPy3k || isPyPy;
-  doCheck = false;
-
-  src = fetchurl {
-    url = "mirror://sourceforge/wxpython/wxPython-src-${version}.tar.bz2";
-    sha256 = "0qfzx3sqx4mwxv99sfybhsij4b5pc03ricl73h4vhkzazgjjjhfm";
-  };
-
-  dontUseSetuptoolsBuild = true;
-  dontUsePipInstall = true;
-
-  hardeningDisable = [ "format" ];
-
-  nativeBuildInputs = [ pkg-config ]
-    ++ (lib.optionals (!stdenv.isDarwin) [ wxGTK libX11 ])
-    ++ (lib.optionals stdenv.isDarwin [ wxmac ]);
-
-  buildInputs = [ ]
-    ++ (lib.optionals (!stdenv.isDarwin) [  (wxGTK.gtk) ])
-    ++ (lib.optionals stdenv.isDarwin (with darwin.apple_sdk.frameworks; [
-      ApplicationServices
-      AudioToolbox
-      CFNetwork
-      Carbon
-      Cocoa
-      CoreGraphics
-      CoreServices
-      CoreText
-      DiskArbitration
-      IOKit
-      ImageIO
-      OpenGL
-      Security
-    ]))
-    ++ (lib.optional openglSupport pyopengl);
-
-  preConfigure = ''
-    cd wxPython
-    # remove wxPython's darwin hack that interference with python-2.7-distutils-C++.patch
-    substituteInPlace config.py \
-      --replace "distutils.unixccompiler.UnixCCompiler = MyUnixCCompiler" ""
-    # set the WXPREFIX to $out instead of the storepath of wxwidgets
-    substituteInPlace config.py \
-      --replace "WXPREFIX   = getWxConfigValue('--prefix')" "WXPREFIX   = '$out'"
-    # this check is supposed to only return false on older systems running non-framework python
-    substituteInPlace src/osx_cocoa/_core_wrap.cpp \
-      --replace "return wxPyTestDisplayAvailable();" "return true;"
-  '' + lib.optionalString (!stdenv.isDarwin) ''
-    substituteInPlace wx/lib/wxcairo.py \
-      --replace 'cairoLib = None' 'cairoLib = ctypes.CDLL("${cairo}/lib/libcairo.so")'
-    substituteInPlace wx/lib/wxcairo.py \
-      --replace '_dlls = dict()' '_dlls = {k: ctypes.CDLL(v) for k, v in [
-        ("gdk",        "${wxGTK.gtk}/lib/libgtk-x11-2.0.so"),
-        ("pangocairo", "${pango.out}/lib/libpangocairo-1.0.so"),
-        ("appsvc",     None)
-      ]}'
-  '';
-
-  buildPhase = "";
-
-  installPhase = ''
-    ${python.interpreter} setup.py install WXPORT=${if stdenv.isDarwin then "osx_cocoa" else "gtk2"} NO_HEADERS=0 BUILD_GLCANVAS=${if openglSupport then "1" else "0"} UNICODE=1 --prefix=$out
-    wrapPythonPrograms
-  '';
-
-  passthru = { inherit wxGTK openglSupport; };
-}
diff --git a/pkgs/tools/misc/csvs-to-sqlite/default.nix b/pkgs/tools/misc/csvs-to-sqlite/default.nix
index 1deae6b3f833..736cc1c3dc5a 100644
--- a/pkgs/tools/misc/csvs-to-sqlite/default.nix
+++ b/pkgs/tools/misc/csvs-to-sqlite/default.nix
@@ -8,7 +8,13 @@ let
   python = python3.override {
     packageOverrides = self: super: {
       # Use click 7
-      click = self.callPackage ../../../development/python2-modules/click/default.nix { };
+      click = super.click.overridePythonAttrs (old: rec {
+        version = "7.1.2";
+        src = old.src.override {
+          inherit version;
+          sha256 = "d2b5255c7c6349bc1bd1e59e08cd12acbbd63ce649f2588755783aa94dfb6b1a";
+        };
+      });
     };
   };
 in with python.pkgs; buildPythonApplication rec {
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 2707fce25485..6894ed5335cb 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -267,6 +267,7 @@ mapAliases ({
   cudnn_cudatoolkit_9_0 = throw "cudnn_cudatoolkit_9_0 has been removed in favor of newer versions"; # Added 2021-04-18
   cudnn_cudatoolkit_9_1 = throw "cudnn_cudatoolkit_9_1 has been removed in favor of newer versions"; # Added 2021-04-18
   cudnn_cudatoolkit_9_2 = throw "cudnn_cudatoolkit_9_2 has been removed in favor of newer versions"; # Added 2021-04-18
+  cura_stable = throw "cura_stable was removed because it was broken and used Python 2"; # added 2022-06-05
   curl_unix_socket = throw "curl_unix_socket has been dropped due to the lack of maintanence from upstream since 2015"; # Added 2022-06-02
   cutensor = throw "cutensor is now part of cudaPackages*"; # Added 2022-04-04
   cutensor_cudatoolkit_10 = throw "cutensor* is now part of cudaPackages*"; # Added 2022-04-04
@@ -1226,6 +1227,7 @@ mapAliases ({
   s6Networking = throw "'s6Networking' has been renamed to/replaced by 's6-networking'"; # Converted to throw 2022-02-22
   s6PortableUtils = throw "'s6PortableUtils' has been renamed to/replaced by 's6-portable-utils'"; # Converted to throw 2022-02-22
   sagemath = throw "'sagemath' has been renamed to/replaced by 'sage'"; # Converted to throw 2022-02-22
+  salut_a_toi = throw "salut_a_toi was removed because it was broken and used Python 2"; # added 2022-06-05
   sam = throw "'sam' has been renamed to/replaced by 'deadpixi-sam'"; # Converted to throw 2022-02-22
   samsungUnifiedLinuxDriver = throw "'samsungUnifiedLinuxDriver' has been renamed to/replaced by 'samsung-unified-linux-driver'"; # Converted to throw 2022-02-22
   sane-backends-git = sane-backends; # Added 2021-02-19
@@ -1588,6 +1590,7 @@ mapAliases ({
   todolist = throw "todolist is now ultralist"; # Added 2020-12-27
   tor-browser-bundle = throw "tor-browser-bundle was removed because it was out of date and inadequately maintained. Please use tor-browser-bundle-bin instead"; # Added 2020-01-10
   tor-browser-unwrapped = throw "tor-browser-unwrapped was removed because it was out of date and inadequately maintained. Please use tor-browser-bundle-bin instead"; # Added 2020-01-10
+  torchat = throw "torchat was removed because it was broken and requires Python 2"; # added 2022-06-05
   ttyrec = ovh-ttyrec; # Added 2021-01-02
   zplugin = zinit; # Added 2021-01-30
 
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 5683a5368379..bd878b1669ca 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -10104,8 +10104,6 @@ with pkgs;
 
   salt = callPackage ../tools/admin/salt {};
 
-  salut_a_toi = callPackage ../applications/networking/instant-messengers/salut-a-toi {};
-
   samim-fonts = callPackage ../data/fonts/samim-fonts {};
 
   saml2aws = callPackage ../tools/security/saml2aws {
@@ -29653,9 +29651,6 @@ with pkgs;
   };
 
   curaengine_stable = callPackage ../applications/misc/curaengine/stable.nix { };
-  cura_stable = callPackage ../applications/misc/cura/stable.nix {
-    curaengine = curaengine_stable;
-  };
 
   curaengine = callPackage ../applications/misc/curaengine { inherit (python3.pkgs) libarcus; };
 
@@ -30073,8 +30068,6 @@ with pkgs;
 
   topydo = callPackage ../applications/misc/topydo {};
 
-  torchat = callPackage ../applications/networking/instant-messengers/torchat { };
-
   torrential = callPackage ../applications/networking/p2p/torrential { };
 
   tortoisehg = callPackage ../applications/version-management/tortoisehg { };
diff --git a/pkgs/top-level/python2-packages.nix b/pkgs/top-level/python2-packages.nix
index c915fc5c8c50..717c16785704 100644
--- a/pkgs/top-level/python2-packages.nix
+++ b/pkgs/top-level/python2-packages.nix
@@ -18,8 +18,6 @@ with self; with super; {
 
   cheetah = callPackage ../development/python2-modules/cheetah { };
 
-  click = callPackage ../development/python2-modules/click { };
-
   configparser = callPackage ../development/python2-modules/configparser { };
 
   construct = callPackage ../development/python2-modules/construct { };
@@ -28,18 +26,10 @@ with self; with super; {
 
   coverage = callPackage ../development/python2-modules/coverage { };
 
-  cryptography = callPackage ../development/python2-modules/cryptography { };
-
-  decorator = callPackage ../development/python2-modules/decorator { };
-
   enum = callPackage ../development/python2-modules/enum { };
 
   filelock =  callPackage ../development/python2-modules/filelock { };
 
-  flask = callPackage ../development/python2-modules/flask { };
-
-  freezegun = callPackage ../development/python2-modules/freezegun { };
-
   futures = callPackage ../development/python2-modules/futures { };
 
   google-apputils = callPackage ../development/python2-modules/google-apputils { };
@@ -54,16 +44,8 @@ with self; with super; {
 
   importlib-metadata = callPackage ../development/python2-modules/importlib-metadata { };
 
-  ipaddr = callPackage ../development/python2-modules/ipaddr { };
-
-  itsdangerous = callPackage ../development/python2-modules/itsdangerous { };
-
   jinja2 = callPackage ../development/python2-modules/jinja2 { };
 
-  libcloud = callPackage ../development/python2-modules/libcloud { };
-
-  lpod = callPackage ../development/python2-modules/lpod { };
-
   marisa = callPackage ../development/python2-modules/marisa {
     inherit (pkgs) marisa;
   };
@@ -110,8 +92,6 @@ with self; with super; {
 
   pygtk = callPackage ../development/python2-modules/pygtk { };
 
-  pyjwt = callPackage ../development/python2-modules/pyjwt { };
-
   pyparsing = callPackage ../development/python2-modules/pyparsing { };
 
   pyroma = callPackage ../development/python2-modules/pyroma { };
@@ -160,20 +140,6 @@ with self; with super; {
 
   typing = callPackage ../development/python2-modules/typing { };
 
-  urllib3 = callPackage ../development/python2-modules/urllib3 { };
-
-  werkzeug = callPackage ../development/python2-modules/werkzeug { };
-
-  wsproto = callPackage ../development/python2-modules/wsproto { };
-
-  wxPython30 = callPackage ../development/python2-modules/wxPython {
-    wxGTK = pkgs.wxGTK30;
-  };
-
-  wxPython = self.wxPython30;
-
-  vcrpy = callPackage ../development/python2-modules/vcrpy { };
-
   zeek = disabled super.zeek;
 
   zipp = callPackage ../development/python2-modules/zipp { };