diff --git a/pkgs/development/python-modules/pynetdicom/default.nix b/pkgs/development/python-modules/pynetdicom/default.nix
index d5126f11169c..5c63fcae29ab 100644
--- a/pkgs/development/python-modules/pynetdicom/default.nix
+++ b/pkgs/development/python-modules/pynetdicom/default.nix
@@ -3,19 +3,18 @@
   stdenv,
   buildPythonPackage,
   fetchFromGitHub,
-  fetchpatch,
+  poetry-core,
   pydicom,
   pyfakefs,
   pytestCheckHook,
   pythonAtLeast,
   pythonOlder,
-  setuptools,
   sqlalchemy,
 }:
 
 buildPythonPackage rec {
   pname = "pynetdicom";
-  version = "2.0.2";
+  version = "2.1.0";
   pyproject = true;
 
   disabled = pythonOlder "3.7";
@@ -24,30 +23,10 @@ buildPythonPackage rec {
     owner = "pydicom";
     repo = "pynetdicom";
     rev = "refs/tags/v${version}";
-    hash = "sha256-/JWQUtFBW4uqCbs/nUxj1pRBfTCXV4wcqTkqvzpdFrM=";
+    hash = "sha256-gAgNSvNn5VsctqhbT/CzFVhwCEpZwGb1pOh0JwkuAW8=";
   };
 
-  patches = [
-    (fetchpatch {
-      name = "fix-python-3.11-test-attribute-errors.patch";
-      url = "https://github.com/pydicom/pynetdicom/pull/754/commits/2126bd932d6dfb3f07045eb9400acb7eaa1b3069.patch";
-      hash = "sha256-t6Lg0sTZSWIE5q5pkBvEoHDQ+cklDn8SgNBcFk1myp4=";
-    })
-    (fetchpatch {
-      # https://github.com/pydicom/pynetdicom/pull/848
-      name = "replace-setup-with-setup_method1.patch";
-      url = "https://github.com/pydicom/pynetdicom/commit/09b4e0901445d46868668bc69a7b4f7f00cf6cbb.patch";
-      hash = "sha256-1ea1A/LU6qY+hd23b6H4OkKHQ0hI2/MYgBgZUZE0kRU=";
-    })
-    (fetchpatch {
-      # https://github.com/pydicom/pynetdicom/pull/848
-      name = "replace-setup-with-setup_method2.patch";
-      url = "https://github.com/pydicom/pynetdicom/commit/3966c2d749eeda718caccf9a88a0495d1823825d.patch";
-      hash = "sha256-C4MSfwwxDgr5T0XQMlR5j2wElPu83TqPhjyNDvfBjJs=";
-    })
-  ];
-
-  build-system = [ setuptools ];
+  build-system = [ poetry-core ];
 
   dependencies = [ pydicom ];