diff --git a/pkgs/development/python-modules/pybind11-protobuf/default.nix b/pkgs/development/python-modules/pybind11-protobuf/default.nix
new file mode 100644
index 000000000000..c8acae9e45b4
--- /dev/null
+++ b/pkgs/development/python-modules/pybind11-protobuf/default.nix
@@ -0,0 +1,76 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  fetchpatch,
+  cmake,
+  abseil-cpp_202301,
+  protobuf_23,
+  pybind11,
+}:
+
+buildPythonPackage {
+  pname = "pybind11-protobuf";
+  version = "0-unstable-2024-01-04";
+  pyproject = false;
+
+  src = fetchFromGitHub {
+    owner = "pybind";
+    repo = "pybind11_protobuf";
+    rev = "3b11990a99dea5101799e61d98a82c4737d240cc";
+    hash = "sha256-saeBxffAbDoHI/YvLatSubpdch9vb5DAfp/Bz3MC8ps=";
+  };
+
+  patches = [
+    (fetchpatch {
+      name = "0001-Make-protobuf-python_api-fully-optional.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0001-Make-protobuf-python_api-fully-optional.patch?rev=1";
+      hash = "sha256-gUeM/7R2kC5DaGKtot9AyG9CyCUHZt5s88dfEtj4b5E=";
+    })
+    (fetchpatch {
+      name = "0002-Add-ENABLE_PYPROTO_API-option-to-CMake-build-clean-u.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0002-Add-ENABLE_PYPROTO_API-option-to-CMake-build-clean-u.patch?rev=1";
+      hash = "sha256-2Wh8XxVXD/RBmkVP4XTJt8gCWrn/zII9h2Cjo6n6dI0=";
+    })
+    (fetchpatch {
+      name = "0003-Make-the-pybind11_-_proto_caster-libraries-STATIC.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0003-Make-the-pybind11_-_proto_caster-libraries-STATIC.patch?rev=1";
+      hash = "sha256-4sa3TD9qjEjHFhxZa/87fiWLJhehNYY2xc3i0jeSHeA=";
+    })
+    (fetchpatch {
+      name = "0004-Fix-handling-of-external-dependencies-allow-forcing-.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0004-Fix-handling-of-external-dependencies-allow-forcing-.patch?rev=1";
+      hash = "sha256-ifqOVU/Lzed+B+8rL6u12TjopA3iYPYDW05QV6W9SAQ=";
+    })
+    (fetchpatch {
+      name = "0005-Build-and-run-the-test-cases.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0005-Build-and-run-the-test-cases.patch?rev=1";
+      hash = "sha256-xTiTGS6AsXCJBcyno7IfQd7P7wH51XoeMCEiT6OcUUY=";
+    })
+    (fetchpatch {
+      name = "0006-Add-install-target-for-CMake-builds.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0006-Add-install-target-for-CMake-builds.patch?rev=1";
+      hash = "sha256-2gJgQGFMB7ihftv4vKEe+ES0wofwaCSzsQm3cAAzXrg=";
+    })
+    (fetchpatch {
+      name = "0007-CMake-Use-Python-Module.patch";
+      url = "https://build.opensuse.org/public/source/openSUSE:Factory/pybind11_protobuf/0007-CMake-Use-Python-Module.patch?rev=1";
+      hash = "sha256-A1dhfh31FMBHBdCfoYmQrInZvO/DeuVMUL57PpUHYfA=";
+    })
+  ];
+
+  nativeBuildInputs = [ cmake ];
+
+  buildInputs = [
+    abseil-cpp_202301
+    protobuf_23
+    pybind11
+  ];
+
+  meta = {
+    description = "Pybind11 bindings for Google's Protocol Buffers";
+    homepage = "https://github.com/pybind/pybind11_protobuf";
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ wegank ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 2e21198bb84d..fbf0110b67ab 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -11752,6 +11752,8 @@ self: super: with self; {
 
   pybind11-abseil = callPackage ../development/python-modules/pybind11-abseil { };
 
+  pybind11-protobuf = callPackage ../development/python-modules/pybind11-protobuf { };
+
   pybind11-stubgen = callPackage ../development/python-modules/pybind11-stubgen { };
 
   pybindgen = callPackage ../development/python-modules/pybindgen { };