diff --git a/pkgs/applications/misc/lenmus/default.nix b/pkgs/applications/misc/lenmus/default.nix
index 023045d67917..80da168cdafe 100644
--- a/pkgs/applications/misc/lenmus/default.nix
+++ b/pkgs/applications/misc/lenmus/default.nix
@@ -1,9 +1,10 @@
 { lib
 , stdenv
-, pkg-config
 , fetchFromGitHub
 , fetchpatch
 , cmake
+, pkg-config
+, makeWrapper
 , boost
 , portmidi
 , sqlite
@@ -11,40 +12,40 @@
 , libpng
 , pngpp
 , zlib
-, wxGTK30
+, wxGTK32
 , wxsqlite3
+, fluidsynth
+, fontconfig
+, darwin
+, soundfont-fluid
+, openlilylib-fonts
 }:
 
+let
+  inherit (darwin.apple_sdk.frameworks) Cocoa;
+in
 stdenv.mkDerivation rec {
   pname = "lenmus";
-  version = "5.4.2";
+  version = "6.0.1";
 
   src = fetchFromGitHub {
     owner = "lenmus";
     repo = "lenmus";
     rev = "Release_${version}";
-    sha256 = "1n639xr1qxx6rhqs0c6sjxp3bv8cwkmw1vfk1cji7514gj2a9v3p";
+    sha256 = "sha256-qegOAc6vs2+6VViDHVjv0q+qjLZyTT7yPF3hFpTt5zE=";
   };
 
-  patches = [
-    (fetchpatch {
-      url = "https://github.com/lenmus/lenmus/commit/421760d84694a0e6e72d0e9b1d4fd30a7e129c6f.patch";
-      sha256 = "1z1wwh0pcr8w1zlr8swx99si9y2kxx5bmavgwvy6bvdhxgm58yqs";
-    })
-    (fetchpatch {
-      url = "https://github.com/lenmus/lenmus/commit/6613d20d4051effc782203c9c6d92962a3f66b5f.patch";
-      sha256 = "01vvzzpamv90jpqbbq1f2m2b4gb9xab9z70am8i41d90nqvg6agn";
-    })
-    (fetchpatch {
-      url = "https://github.com/lenmus/lenmus/commit/37ee8ac9c8faff65a14e8f7ed2bc22e6dc48d91f.patch";
-      includes = [ "src/app/lenmus_midi_wizard.cpp" ];
-      sha256 = "sha256-nlT6ZbSCIXUk2Ufv/SDn2A0Rt+s/7m+7l9HOoQmaIhc=";
-    })
-  ];
+  postPatch = ''
+    substituteInPlace CMakeLists.txt \
+      --replace "/usr" "${placeholder "out"}"
+    sed -i 's/fixup_bundle.*")/")/g' CMakeLists.txt
+  '';
 
   nativeBuildInputs = [
     cmake
     pkg-config
+  ] ++ lib.optionals stdenv.isDarwin [
+    makeWrapper
   ];
 
   buildInputs = [
@@ -55,10 +56,33 @@ stdenv.mkDerivation rec {
     libpng
     pngpp
     zlib
-    wxGTK30
+    wxGTK32
     wxsqlite3
+    fluidsynth
+    fontconfig
+  ] ++ lib.optionals stdenv.isDarwin [
+    Cocoa
   ];
 
+  preConfigure = ''
+    mkdir res/fonts
+    ln -s ${openlilylib-fonts.bravura}/share/lilypond/*/fonts/otf/Bravura.otf res/fonts/Bravura.otf
+    ln -s ${soundfont-fluid}/share/soundfonts/FluidR3_GM2-2.sf2 res/sounds/FluidR3_GM.sf2
+  '';
+
+  cmakeFlags = [
+    "-DCMAKE_INSTALL_PREFIX=${placeholder "out"}"
+    "-DLENMUS_INSTALL_SOUNDFONT=ON"
+    "-DMAN_INSTALL_DIR=${placeholder "out"}/share/man"
+  ];
+
+  postInstall = lib.optionalString stdenv.isDarwin ''
+    mkdir -p $out/{Applications,bin}
+    mv $out/lenmus.app $out/Applications
+    mv $out/Resources $out/Applications/lenmus.app/Contents
+    makeWrapper $out/{Applications/lenmus.app/Contents/MacOS,bin}/lenmus
+  '';
+
   meta = with lib; {
     description = "LenMus Phonascus is a program for learning music";
     longDescription = ''
@@ -69,6 +93,6 @@ stdenv.mkDerivation rec {
     homepage = "http://www.lenmus.org/";
     license = licenses.gpl3Plus;
     maintainers = with maintainers;  [ ramkromberg ];
-    platforms = with platforms; linux;
+    platforms = with platforms; unix;
   };
 }