diff --git a/pkgs/development/python-modules/mdformat-myst/default.nix b/pkgs/development/python-modules/mdformat-myst/default.nix
new file mode 100644
index 000000000000..01a5a327accb
--- /dev/null
+++ b/pkgs/development/python-modules/mdformat-myst/default.nix
@@ -0,0 +1,49 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  flit-core,
+  mdformat,
+  mdformat-footnote,
+  mdformat-frontmatter,
+  mdformat-tables,
+  mdit-py-plugins,
+  ruamel-yaml,
+  pytestCheckHook,
+}:
+
+buildPythonPackage rec {
+  pname = "mdformat-myst";
+  version = "0.2.1";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "executablebooks";
+    repo = "mdformat-myst";
+    tag = "v${version}";
+    hash = "sha256-Ty9QOsOTCNfhdLVuLfD0x63OFfHhODr14i/dhN+Sqnc=";
+  };
+
+  build-system = [ flit-core ];
+
+  dependencies = [
+    mdformat
+    mdformat-footnote
+    mdformat-frontmatter
+    mdformat-tables
+    mdit-py-plugins
+    ruamel-yaml
+  ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
+
+  pythonImportsCheck = [ "mdformat_myst" ];
+
+  meta = {
+    description = "Mdformat plugin for MyST compatibility";
+    homepage = "https://github.com/executablebooks/mdformat-myst";
+    changelog = "https://github.com/executablebooks/mdformat-myst/releases/tag/v${version}/CHANGELOG.md";
+    license = lib.licenses.mit;
+    maintainers = with lib.maintainers; [ mattkang ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 7c4cc55a5389..e65338ef1001 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -7513,6 +7513,7 @@ self: super: with self; {
   mdformat-frontmatter = callPackage ../development/python-modules/mdformat-frontmatter { };
   mdformat-gfm = callPackage ../development/python-modules/mdformat-gfm { };
   mdformat-mkdocs = callPackage ../development/python-modules/mdformat-mkdocs { };
+  mdformat-myst = callPackage ../development/python-modules/mdformat-myst{ };
   mdformat-nix-alejandra = callPackage ../development/python-modules/mdformat-nix-alejandra { };
   mdformat-simple-breaks = callPackage ../development/python-modules/mdformat-simple-breaks { };
   mdformat-tables = callPackage ../development/python-modules/mdformat-tables { };