diff --git a/pkgs/development/python-modules/morecantile/default.nix b/pkgs/development/python-modules/morecantile/default.nix
index 8d0fd9ef7373..2246f96736bd 100644
--- a/pkgs/development/python-modules/morecantile/default.nix
+++ b/pkgs/development/python-modules/morecantile/default.nix
@@ -46,7 +46,22 @@ buildPythonPackage rec {
     rasterio
   ];
 
-  disabledTests = lib.optionals stdenv.hostPlatform.isDarwin [
+  disabledTests = [
+    # AssertionError CLI exists with non-zero error code
+    # This is a regression introduced by https://github.com/NixOS/nixpkgs/pull/448189
+    "test_cli_shapes"
+    "test_cli_shapesWGS84"
+    "test_cli_strict_overlap_contain"
+    "test_cli_tiles_bad_bounds"
+    "test_cli_tiles_geosjon"
+    "test_cli_tiles_implicit_stdin"
+    "test_cli_tiles_multi_bounds"
+    "test_cli_tiles_multi_bounds_seq"
+    "test_cli_tiles_ok"
+    "test_cli_tiles_points"
+    "test_cli_tiles_seq"
+  ]
+  ++ lib.optionals stdenv.hostPlatform.isDarwin [
     # https://github.com/developmentseed/morecantile/issues/156
     "test_tiles_when_tms_bounds_and_provided_bounds_cross_antimeridian"
   ];