diff --git a/pkgs/development/python-modules/httpbin/default.nix b/pkgs/development/python-modules/httpbin/default.nix
index 8359fcf0a096..a5a77a82af29 100644
--- a/pkgs/development/python-modules/httpbin/default.nix
+++ b/pkgs/development/python-modules/httpbin/default.nix
@@ -2,6 +2,7 @@
 , brotlipy
 , buildPythonPackage
 , decorator
+, fetchpatch
 , fetchPypi
 , flask
 , flask-limiter
@@ -22,6 +23,15 @@ buildPythonPackage rec {
     hash = "sha256-y7N3kMkVdfTxV1f0KtQdn3KesifV7b6J5OwXVIbbjfo=";
   };
 
+  patches = [
+    (fetchpatch {
+      # Replaces BaseResponse class with Response class for Werkezug 2.1.0 compatibility
+      # https://github.com/postmanlabs/httpbin/pull/674
+      url = "https://github.com/postmanlabs/httpbin/commit/5cc81ce87a3c447a127e4a1a707faf9f3b1c9b6b.patch";
+      hash = "sha256-SbEWjiqayMFYrbgAPZtSsXqSyCDUz3z127XgcKOcrkE=";
+    })
+  ];
+
   propagatedBuildInputs = [
     brotlipy
     flask