diff --git a/pkgs/development/libraries/grpc/default.nix b/pkgs/development/libraries/grpc/default.nix
index 948048895700..1dd516ec99cf 100644
--- a/pkgs/development/libraries/grpc/default.nix
+++ b/pkgs/development/libraries/grpc/default.nix
@@ -19,11 +19,19 @@
 , arrow-cpp
 }:
 
+# This package should be updated together with all related python grpc packages
+# to ensure compatibility.
+# nixpkgs-update: no auto update
 stdenv.mkDerivation rec {
   pname = "grpc";
   version = "1.66.1"; # N.B: if you change this, please update:
-    # pythonPackages.grpcio-tools
+    # pythonPackages.grpcio
+    # pythonPackages.grpcio-channelz
+    # pythonPackages.grpcio-health-checking
+    # pythonPackages.grpcio-reflection
     # pythonPackages.grpcio-status
+    # pythonPackages.grpcio-testing
+    # pythonPackages.grpcio-tools
 
   src = fetchFromGitHub {
     owner = "grpc";
diff --git a/pkgs/development/python-modules/grpcio-channelz/default.nix b/pkgs/development/python-modules/grpcio-channelz/default.nix
index 4d5662509e06..75c3ade1b51d 100644
--- a/pkgs/development/python-modules/grpcio-channelz/default.nix
+++ b/pkgs/development/python-modules/grpcio-channelz/default.nix
@@ -7,6 +7,9 @@
   protobuf,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-channelz";
   version = "1.66.2";
diff --git a/pkgs/development/python-modules/grpcio-health-checking/default.nix b/pkgs/development/python-modules/grpcio-health-checking/default.nix
index e7b6f49f158b..c96b71d3f5fc 100644
--- a/pkgs/development/python-modules/grpcio-health-checking/default.nix
+++ b/pkgs/development/python-modules/grpcio-health-checking/default.nix
@@ -6,6 +6,9 @@
   protobuf,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-health-checking";
   version = "1.66.2";
diff --git a/pkgs/development/python-modules/grpcio-reflection/default.nix b/pkgs/development/python-modules/grpcio-reflection/default.nix
index 35fb1faaeaef..c37492ccf476 100644
--- a/pkgs/development/python-modules/grpcio-reflection/default.nix
+++ b/pkgs/development/python-modules/grpcio-reflection/default.nix
@@ -7,6 +7,9 @@
   protobuf,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-reflection";
   version = "1.66.2";
diff --git a/pkgs/development/python-modules/grpcio-status/default.nix b/pkgs/development/python-modules/grpcio-status/default.nix
index e72822cbd68d..065f4f833ecc 100644
--- a/pkgs/development/python-modules/grpcio-status/default.nix
+++ b/pkgs/development/python-modules/grpcio-status/default.nix
@@ -8,6 +8,9 @@
   pythonOlder,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-status";
   version = "1.66.1";
diff --git a/pkgs/development/python-modules/grpcio-testing/default.nix b/pkgs/development/python-modules/grpcio-testing/default.nix
index cabad7a8cfbe..0d38efffbc14 100644
--- a/pkgs/development/python-modules/grpcio-testing/default.nix
+++ b/pkgs/development/python-modules/grpcio-testing/default.nix
@@ -8,6 +8,9 @@
   setuptools,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-testing";
   version = "1.66.2";
diff --git a/pkgs/development/python-modules/grpcio-tools/default.nix b/pkgs/development/python-modules/grpcio-tools/default.nix
index a61999ef5b78..f5c477eb3a87 100644
--- a/pkgs/development/python-modules/grpcio-tools/default.nix
+++ b/pkgs/development/python-modules/grpcio-tools/default.nix
@@ -7,6 +7,9 @@
   setuptools,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio-tools";
   version = "1.66.1";
diff --git a/pkgs/development/python-modules/grpcio/default.nix b/pkgs/development/python-modules/grpcio/default.nix
index 5dc26d50be2b..2502643370e6 100644
--- a/pkgs/development/python-modules/grpcio/default.nix
+++ b/pkgs/development/python-modules/grpcio/default.nix
@@ -16,6 +16,9 @@
   zlib,
 }:
 
+# This package should be updated together with the main grpc package and other
+# related python grpc packages.
+# nixpkgs-update: no auto update
 buildPythonPackage rec {
   pname = "grpcio";
   format = "setuptools";