diff --git a/pkgs/development/tools/misc/gdb/default.nix b/pkgs/development/tools/misc/gdb/default.nix
index 29bc6e601e65..1c4d6506b72e 100644
--- a/pkgs/development/tools/misc/gdb/default.nix
+++ b/pkgs/development/tools/misc/gdb/default.nix
@@ -9,6 +9,7 @@
 , pythonSupport ? stdenv.hostPlatform == stdenv.buildPlatform && !stdenv.hostPlatform.isCygwin, python3 ? null
 , enableDebuginfod ? false, elfutils
 , guile ? null
+, hostCpuOnly ? false
 , safePaths ? [
    # $debugdir:$datadir/auto-load are whitelisted by default by GDB
    "$debugdir" "$datadir/auto-load"
@@ -27,7 +28,7 @@ in
 assert pythonSupport -> python3 != null;
 
 stdenv.mkDerivation rec {
-  pname = targetPrefix + basename;
+  pname = targetPrefix + basename + lib.optionalString hostCpuOnly "-host-cpu-only";
   version = "13.1";
 
   src = fetchurl {
@@ -94,7 +95,8 @@ stdenv.mkDerivation rec {
     "--program-prefix=${targetPrefix}"
 
     "--disable-werror"
-    "--enable-targets=all" "--enable-64-bit-bfd"
+  ] ++ lib.optional (!hostCpuOnly) "--enable-targets=all" ++ [
+    "--enable-64-bit-bfd"
     "--disable-install-libbfd"
     "--disable-shared" "--enable-static"
     "--with-system-zlib"
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 27b79680848f..9484dc4d7fd3 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -19102,6 +19102,8 @@ with pkgs;
     guile = null;
   };
 
+  gdbHostCpuOnly = gdb.override { hostCpuOnly = true; };
+
   gf = callPackage ../development/tools/misc/gf { };
 
   java-language-server = callPackage ../development/tools/java/java-language-server { };