diff --git a/pkgs/development/python-modules/py-ecc/default.nix b/pkgs/development/python-modules/py-ecc/default.nix
index 6e2683104775..d7769ea4873d 100644
--- a/pkgs/development/python-modules/py-ecc/default.nix
+++ b/pkgs/development/python-modules/py-ecc/default.nix
@@ -5,6 +5,7 @@
 , eth-typing
 , eth-utils
 , pytestCheckHook
+, pythonAtLeast
 , pythonOlder
 , setuptools
 }:
@@ -36,6 +37,18 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
+  disabledTests = lib.optionals (pythonAtLeast "3.12") [
+    # https://github.com/ethereum/py_ecc/issues/133
+    "test_FQ2_object"
+    "test_pairing_bilinearity_on_G1"
+    "test_pairing_bilinearity_on_G2"
+    "test_pairing_composit_check"
+    "test_pairing_is_non_degenerate"
+    "test_pairing_negative_G1"
+    "test_pairing_negative_G2"
+    "test_pairing_output_order"
+  ];
+
   pythonImportsCheck = [ "py_ecc" ];
 
   meta = with lib; {