diff --git a/pkgs/by-name/op/openmpi/package.nix b/pkgs/by-name/op/openmpi/package.nix
index 3e39d13d8a51..791a78b05b17 100644
--- a/pkgs/by-name/op/openmpi/package.nix
+++ b/pkgs/by-name/op/openmpi/package.nix
@@ -57,6 +57,14 @@ stdenv.mkDerivation (finalAttrs: {
       url = "https://github.com/open-mpi/ompi/commit/4d4f7212decd0d0ca719688b15dc9b3ee7553a52.patch";
       hash = "sha256-Mb8qXtAUhAQ90v0SdL24BoTASsKRq2Gu8nYqoeSc9DI=";
     })
+    # This patch can be removed with the next openmpi update (>5.0.6)
+    # See https://github.com/open-mpi/ompi/issues/12924 and https://github.com/open-mpi/ompi/pull/12934
+    # Fix the size_t/int parameter compile error in coll/cuda
+    (fetchpatch {
+      name = "fix-size-t-int-parameter";
+      url = "https://github.com/open-mpi/ompi/commit/399f69d68735839d379913a5433ea81dbdbd98bf.patch";
+      hash = "sha256-TbB73a419v5JGkiyBAwe/t+6g+pzaR15yAZhdbJIXG4=";
+    })
   ];
 
   postPatch = ''
@@ -137,6 +145,7 @@ stdenv.mkDerivation (finalAttrs: {
     # https://github.com/openucx/ucx
     # https://www.open-mpi.org/faq/?category=buildcuda
     (lib.withFeatureAs cudaSupport "cuda" (lib.getDev cudaPackages.cuda_cudart))
+    (lib.withFeatureAs cudaSupport "cuda-libdir" "${cudaPackages.cuda_cudart.stubs}/lib")
     (lib.enableFeature cudaSupport "dlopen")
     (lib.withFeatureAs fabricSupport "psm2" (lib.getDev libpsm2))
     (lib.withFeatureAs fabricSupport "ofi" (lib.getDev libfabric))