diff --git a/pkgs/development/python-modules/clize/default.nix b/pkgs/development/python-modules/clize/default.nix
index 4f9a562543b9..75c4513d1e3a 100644
--- a/pkgs/development/python-modules/clize/default.nix
+++ b/pkgs/development/python-modules/clize/default.nix
@@ -7,7 +7,6 @@
 , attrs
 , od
 , docutils
-, repeated_test
 , pygments
 , unittest2
 , pytestCheckHook
@@ -22,11 +21,13 @@ buildPythonPackage rec {
     sha256 = "3177a028e4169d8865c79af82bdd441b24311d4bd9c0ae8803641882d340a51d";
   };
 
+  # repeated_test no longer exists in nixpkgs
+  # also see: https://github.com/epsy/clize/issues/74
+  doCheck = false;
   checkInputs = [
     pytestCheckHook
     python-dateutil
     pygments
-    repeated_test
     unittest2
   ];
 
diff --git a/pkgs/development/python-modules/od/default.nix b/pkgs/development/python-modules/od/default.nix
index aa275cb27a69..698795c75bae 100644
--- a/pkgs/development/python-modules/od/default.nix
+++ b/pkgs/development/python-modules/od/default.nix
@@ -1,4 +1,4 @@
-{ lib, buildPythonPackage, fetchPypi, unittest2, repeated_test }:
+{ lib, buildPythonPackage, fetchPypi, unittest2 }:
 
 buildPythonPackage rec {
   pname = "od";
@@ -9,8 +9,10 @@ buildPythonPackage rec {
     sha256 = "1az30snc3w6s4k1pi7mspcv8y0kp3ihf3ly44z517nszmz9lrjfi";
   };
 
+  # repeated_test no longer exists in nixpkgs
+  # also see: https://github.com/epsy/od/issues/1
+  doCheck = false;
   checkInputs = [
-    repeated_test
     unittest2
   ];
 
diff --git a/pkgs/development/python-modules/repeated_test/default.nix b/pkgs/development/python-modules/repeated_test/default.nix
deleted file mode 100644
index 2c51238e19b5..000000000000
--- a/pkgs/development/python-modules/repeated_test/default.nix
+++ /dev/null
@@ -1,26 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-, unittest2
-, six
-}:
-
-buildPythonPackage rec {
-  pname = "repeated_test";
-  version = "1.0.1";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "65107444a4945668ab7be6d1a3e1814cee9b2cfc577e7c70381700b11b809d27";
-  };
-
-  buildInputs = [ unittest2 ];
-  propagatedBuildInputs = [ six ];
-
-  meta = with lib; {
-    description = "A quick unittest-compatible framework for repeating a test function over many fixtures";
-    homepage = "https://github.com/epsy/repeated_test";
-    license = licenses.mit;
-  };
-
-}
diff --git a/pkgs/development/python-modules/sigtools/default.nix b/pkgs/development/python-modules/sigtools/default.nix
index b61e64684c86..49ba916b481c 100644
--- a/pkgs/development/python-modules/sigtools/default.nix
+++ b/pkgs/development/python-modules/sigtools/default.nix
@@ -1,7 +1,6 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, repeated_test
 , sphinx
 , mock
 , coverage
@@ -19,11 +18,15 @@ buildPythonPackage rec {
     sha256 = "e7789628ec0d02e421bca76532b0d5da149f96f09e7ed4a5cbf318624b75e949";
   };
 
-  buildInputs = [ repeated_test sphinx mock coverage unittest2 ];
   propagatedBuildInputs = [ funcsigs six ];
 
   patchPhase = ''sed -i s/test_suite="'"sigtools.tests"'"/test_suite="'"unittest2.collector"'"/ setup.py'';
 
+  # repeated_test no longer exists in nixpkgs
+  # Also see: https://github.com/epsy/sigtools/issues/26
+  doCheck = false;
+  checkInputs = [ sphinx mock coverage unittest2 ];
+
   meta = with lib; {
     description = "Utilities for working with 3.3's inspect.Signature objects.";
     homepage = "https://pypi.python.org/pypi/sigtools";
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 5d19c70f03d6..1e74b6c88475 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -87,6 +87,7 @@ mapAliases ({
   python_simple_hipchat = python-simple-hipchat; # added 2021-07-21
   qasm2image = throw "qasm2image is no longer maintained (since November 2018), and is not compatible with the latest pythonPackages.qiskit versions."; # added 2020-12-09
   rdflib-jsonld = throw "rdflib-jsonld is not compatible with rdflib 6"; # added 2021-11-05
+  repeated_test = throw "repeated_test is no longer maintained"; # added 2022-01-11
   requests_toolbelt = requests-toolbelt; # added 2017-09-26
   rotate-backups = throw "rotate-backups was removed in favor of the top-level rotate-backups"; # added 2021-07-01
   ruamel_base = ruamel-base; # added 2021-11-01
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 13a9160dc6d9..5b77053944a6 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8459,8 +8459,6 @@ in {
 
   reparser = callPackage ../development/python-modules/reparser { };
 
-  repeated_test = callPackage ../development/python-modules/repeated_test { };
-
   repocheck = callPackage ../development/python-modules/repocheck { };
 
   reportlab = callPackage ../development/python-modules/reportlab { };