diff --git a/pkgs/development/python-modules/pillow-heif/default.nix b/pkgs/development/python-modules/pillow-heif/default.nix
index 2496bd1b3609..33575ace5508 100644
--- a/pkgs/development/python-modules/pillow-heif/default.nix
+++ b/pkgs/development/python-modules/pillow-heif/default.nix
@@ -55,6 +55,9 @@ buildPythonPackage rec {
     x265
   ];
 
+  # clang-16: error: argument unused during compilation: '-fno-strict-overflow' [-Werror,-Wunused-command-line-argument]
+  env.NIX_CFLAGS_COMPILE = lib.optionalString stdenv.cc.isClang "-Wno-unused-command-line-argument";
+
   propagatedBuildInputs = [
     pillow
   ];