diff --git a/pkgs/development/python-modules/opentelemetry-instrumentation-wsgi/default.nix b/pkgs/development/python-modules/opentelemetry-instrumentation-wsgi/default.nix
new file mode 100644
index 000000000000..b50674ea1b68
--- /dev/null
+++ b/pkgs/development/python-modules/opentelemetry-instrumentation-wsgi/default.nix
@@ -0,0 +1,53 @@
+{ lib
+, buildPythonPackage
+, pythonOlder
+, fetchFromGitHub
+, hatchling
+, opentelemetry-api
+, opentelemetry-instrumentation
+, opentelemetry-semantic-conventions
+, opentelemetry-test-utils
+, opentelemetry-util-http
+, pytestCheckHook
+}:
+
+buildPythonPackage rec {
+  pname = "opentelemetry-instrumentation-wsgi";
+  version = "0.39b0";
+  disabled = pythonOlder "3.7";
+
+  src = fetchFromGitHub {
+    owner = "open-telemetry";
+    repo = "opentelemetry-python-contrib";
+    rev = "refs/tags/v${version}";
+    hash = "sha256-DBZGXY8Y208YC/guk0qUB04UA/JFAtiv3kjsikskTRs=";
+    sparseCheckout = [ "/instrumentation/${pname}" ];
+  } + "/instrumentation/${pname}";
+
+  format = "pyproject";
+
+  nativeBuildInputs = [
+    hatchling
+  ];
+
+  propagatedBuildInputs = [
+    opentelemetry-instrumentation
+    opentelemetry-api
+    opentelemetry-semantic-conventions
+    opentelemetry-util-http
+  ];
+
+  nativeCheckInputs = [
+    opentelemetry-test-utils
+    pytestCheckHook
+  ];
+
+  pythonImportsCheck = [ "opentelemetry.instrumentation.wsgi" ];
+
+  meta = with lib; {
+    homepage = "https://github.com/open-telemetry/opentelemetry-python-contrib/blob/main/instrumentation/opentelemetry-instrumentation-wsgi";
+    description = "WSGI Middleware for OpenTelemetry";
+    license = licenses.asl20;
+    maintainers = teams.deshaw.members;
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 1ad1f4df6719..fee4f669ab7e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -7108,6 +7108,8 @@ self: super: with self; {
 
   opentelemetry-instrumentation = callPackage ../development/python-modules/opentelemetry-instrumentation { };
 
+  opentelemetry-instrumentation-wsgi = callPackage ../development/python-modules/opentelemetry-instrumentation-wsgi { };
+
   opentelemetry-proto = callPackage ../development/python-modules/opentelemetry-proto { };
 
   opentelemetry-semantic-conventions = callPackage ../development/python-modules/opentelemetry-semantic-conventions { };