diff --git a/pkgs/development/compilers/ghc/8.10.7.nix b/pkgs/development/compilers/ghc/8.10.7.nix
index 49fe3417a442..3f64b4fef53e 100644
--- a/pkgs/development/compilers/ghc/8.10.7.nix
+++ b/pkgs/development/compilers/ghc/8.10.7.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, pkgsBuildTarget, targetPackages
+{ lib, stdenv, pkgsBuildTarget, pkgsHostTarget, targetPackages
 
 # build-tools
 , bootPkgs
@@ -143,6 +143,14 @@ let
   ];
 
 in
+
+# C compiler, bintools and LLVM are used at build time, but will also leak into
+# the resulting GHC's settings file and used at runtime. This means that we are
+# currently only able to build GHC if hostPlatform == buildPlatform.
+assert targetCC == pkgsHostTarget.targetPackages.stdenv.cc;
+assert buildTargetLlvmPackages.llvm == llvmPackages.llvm;
+assert stdenv.targetPlatform.isDarwin -> buildTargetLlvmPackages.clang == llvmPackages.clang;
+
 stdenv.mkDerivation (rec {
   version = "8.10.7";
   pname = "${targetPrefix}ghc${variantSuffix}";
diff --git a/pkgs/development/compilers/ghc/8.8.4.nix b/pkgs/development/compilers/ghc/8.8.4.nix
index 9232eac0ce18..438e47f4a509 100644
--- a/pkgs/development/compilers/ghc/8.8.4.nix
+++ b/pkgs/development/compilers/ghc/8.8.4.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, pkgsBuildTarget, targetPackages
+{ lib, stdenv, pkgsBuildTarget, pkgsHostTarget, targetPackages
 
 # build-tools
 , bootPkgs
@@ -151,6 +151,14 @@ let
   ];
 
 in
+
+# C compiler, bintools and LLVM are used at build time, but will also leak into
+# the resulting GHC's settings file and used at runtime. This means that we are
+# currently only able to build GHC if hostPlatform == buildPlatform.
+assert targetCC == pkgsHostTarget.targetPackages.stdenv.cc;
+assert buildTargetLlvmPackages.llvm == llvmPackages.llvm;
+assert stdenv.targetPlatform.isDarwin -> buildTargetLlvmPackages.clang == llvmPackages.clang;
+
 stdenv.mkDerivation (rec {
   version = "8.8.4";
   pname = "${targetPrefix}ghc${variantSuffix}";
diff --git a/pkgs/development/compilers/ghc/9.0.1.nix b/pkgs/development/compilers/ghc/9.0.1.nix
index fda5de7c2531..aea65aa479ef 100644
--- a/pkgs/development/compilers/ghc/9.0.1.nix
+++ b/pkgs/development/compilers/ghc/9.0.1.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, pkgsBuildTarget, targetPackages
+{ lib, stdenv, pkgsBuildTarget, pkgsHostTarget, targetPackages
 
 # build-tools
 , bootPkgs
@@ -138,6 +138,14 @@ let
   ];
 
 in
+
+# C compiler, bintools and LLVM are used at build time, but will also leak into
+# the resulting GHC's settings file and used at runtime. This means that we are
+# currently only able to build GHC if hostPlatform == buildPlatform.
+assert targetCC == pkgsHostTarget.targetPackages.stdenv.cc;
+assert buildTargetLlvmPackages.llvm == llvmPackages.llvm;
+assert stdenv.targetPlatform.isDarwin -> buildTargetLlvmPackages.clang == llvmPackages.clang;
+
 stdenv.mkDerivation (rec {
   version = "9.0.1";
   pname = "${targetPrefix}ghc${variantSuffix}";
diff --git a/pkgs/development/compilers/ghc/9.2.1.nix b/pkgs/development/compilers/ghc/9.2.1.nix
index 16543ce49bcd..ad5cd4bbb807 100644
--- a/pkgs/development/compilers/ghc/9.2.1.nix
+++ b/pkgs/development/compilers/ghc/9.2.1.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, pkgsBuildTarget, targetPackages
+{ lib, stdenv, pkgsBuildTarget, pkgsHostTarget, targetPackages
 
 # build-tools
 , bootPkgs
@@ -139,6 +139,14 @@ let
   ];
 
 in
+
+# C compiler, bintools and LLVM are used at build time, but will also leak into
+# the resulting GHC's settings file and used at runtime. This means that we are
+# currently only able to build GHC if hostPlatform == buildPlatform.
+assert targetCC == pkgsHostTarget.targetPackages.stdenv.cc;
+assert buildTargetLlvmPackages.llvm == llvmPackages.llvm;
+assert stdenv.targetPlatform.isDarwin -> buildTargetLlvmPackages.clang == llvmPackages.clang;
+
 stdenv.mkDerivation (rec {
   version = "9.2.1";
   pname = "${targetPrefix}ghc${variantSuffix}";
diff --git a/pkgs/development/compilers/ghc/head.nix b/pkgs/development/compilers/ghc/head.nix
index 35e52befe200..79c72de63f26 100644
--- a/pkgs/development/compilers/ghc/head.nix
+++ b/pkgs/development/compilers/ghc/head.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, pkgsBuildTarget, targetPackages
+{ lib, stdenv, pkgsBuildTarget, pkgsHostTarget, targetPackages
 
 # build-tools
 , bootPkgs
@@ -152,6 +152,14 @@ let
   ];
 
 in
+
+# C compiler, bintools and LLVM are used at build time, but will also leak into
+# the resulting GHC's settings file and used at runtime. This means that we are
+# currently only able to build GHC if hostPlatform == buildPlatform.
+assert targetCC == pkgsHostTarget.targetPackages.stdenv.cc;
+assert buildTargetLlvmPackages.llvm == llvmPackages.llvm;
+assert stdenv.targetPlatform.isDarwin -> buildTargetLlvmPackages.clang == llvmPackages.clang;
+
 stdenv.mkDerivation (rec {
   inherit version;
   inherit (src) rev;