diff --git a/pkgs/development/python-modules/rdkit/default.nix b/pkgs/development/python-modules/rdkit/default.nix
index fd66dd16cb90..77cd25503084 100644
--- a/pkgs/development/python-modules/rdkit/default.nix
+++ b/pkgs/development/python-modules/rdkit/default.nix
@@ -117,11 +117,11 @@ buildPythonPackage rec {
     (lib.cmakeBool "RDK_BUILD_INCHI_SUPPORT" true)
     (lib.cmakeBool "RDK_BUILD_MAEPARSER_SUPPORT" true)
     (lib.cmakeBool "RDK_BUILD_THREADSAFE_SSS" true)
+    (lib.cmakeBool "RDK_BUILD_XYZ2MOL_SUPPORT" true)
     (lib.cmakeBool "RDK_BUILD_YAEHMOP_SUPPORT" true)
     (lib.cmakeBool "RDK_INSTALL_INTREE" false)
     (lib.cmakeBool "RDK_INSTALL_STATIC_LIBS" false)
     (lib.cmakeBool "RDK_TEST_MULTITHREADED" true)
-    (lib.cmakeBool "RDK_TEST_MULTITHREADED" true)
     (lib.cmakeBool "RDK_USE_FLEXBISON" false)
     (lib.cmakeBool "RDK_USE_URF" false)
     (lib.cmakeFeature "AVALONTOOLS_DIR" "avalon")
@@ -141,6 +141,7 @@ buildPythonPackage rec {
     "rdkit"
     "rdkit.Chem"
     "rdkit.Chem.AllChem"
+    "rdkit.Chem.rdDetermineBonds"
   ];
 
   meta = with lib; {