diff --git a/pkgs/development/python-modules/tensorflow/bin.nix b/pkgs/development/python-modules/tensorflow/bin.nix
index 4184e3aff02b..221c75112b9b 100644
--- a/pkgs/development/python-modules/tensorflow/bin.nix
+++ b/pkgs/development/python-modules/tensorflow/bin.nix
@@ -22,6 +22,7 @@
 , cudaSupport ? false
 , cudatoolkit
 , cudnn
+, patchelfUnstable
 , zlib
 , python
 , keras-applications
@@ -78,7 +79,8 @@ in buildPythonPackage {
   ] ++ lib.optional (!isPy3k) mock
     ++ lib.optionals (pythonOlder "3.4") [ backports_weakref ];
 
-  nativeBuildInputs = [ wheel ] ++ lib.optional cudaSupport addOpenGLRunpath;
+  # remove patchelfUnstable once patchelf 0.14 with https://github.com/NixOS/patchelf/pull/256 becomes the default
+  nativeBuildInputs = [ wheel ] ++ lib.optional cudaSupport [ addOpenGLRunpath patchelfUnstable ];
 
   preConfigure = ''
     unset SOURCE_DATE_EPOCH
diff --git a/pkgs/development/python-modules/tensorflow/default.nix b/pkgs/development/python-modules/tensorflow/default.nix
index 01af29ceda41..b43ac71ba41e 100644
--- a/pkgs/development/python-modules/tensorflow/default.nix
+++ b/pkgs/development/python-modules/tensorflow/default.nix
@@ -1,5 +1,5 @@
 { stdenv, bazel_3, buildBazelPackage, isPy3k, lib, fetchFromGitHub, symlinkJoin
-, addOpenGLRunpath, fetchpatch
+, addOpenGLRunpath, fetchpatch, patchelfUnstable
 # Python deps
 , buildPythonPackage, pythonOlder, python
 # Python libraries
@@ -465,7 +465,8 @@ in buildPythonPackage {
     tensorflow-tensorboard
   ];
 
-  nativeBuildInputs = lib.optional cudaSupport addOpenGLRunpath;
+  # remove patchelfUnstable once patchelf 0.14 with https://github.com/NixOS/patchelf/pull/256 becomes the default
+  nativeBuildInputs = lib.optional cudaSupport [ addOpenGLRunpath patchelfUnstable ];
 
   postFixup = lib.optionalString cudaSupport ''
     find $out -type f \( -name '*.so' -or -name '*.so.*' \) | while read lib; do
diff --git a/pkgs/development/tools/misc/patchelf/unstable.nix b/pkgs/development/tools/misc/patchelf/unstable.nix
index dd7f4ac881b4..740015dbe984 100644
--- a/pkgs/development/tools/misc/patchelf/unstable.nix
+++ b/pkgs/development/tools/misc/patchelf/unstable.nix
@@ -2,13 +2,13 @@
 
 stdenv.mkDerivation rec {
   name = "patchelf-${version}";
-  version = "2020-07-11";
+  version = "2021-11-16";
 
   src = fetchFromGitHub {
     owner = "NixOS";
     repo = "patchelf";
-    rev = "126372b636733b160e693c9913e871f6755c02e";
-    sha256 = "07cn40ypys5pyc3jfgxvqj7qk5v6m2rr5brnpmxdsl1557ryx226";
+    rev = "a174cf3006baf31e0e9eaa62bc9adead93af63f7";
+    sha256 = "sha256-cKZ4DE70R5XiIqfnIVAl2s7a1bJxaaPpuCmxs3pxFRU=";
   };
 
   # Drop test that fails on musl (?)
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index bca527f6db07..04d93593c3d3 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -9229,15 +9229,15 @@ in {
 
   tensorflow-bin = callPackage ../development/python-modules/tensorflow/bin.nix {
     cudaSupport = pkgs.config.cudaSupport or false;
-    cudatoolkit = pkgs.cudatoolkit_11_0;
-    cudnn = pkgs.cudnn_cudatoolkit_11_0;
+    cudatoolkit = pkgs.cudatoolkit_11_2;
+    cudnn = pkgs.cudnn_cudatoolkit_11_2;
   };
 
   tensorflow-build = callPackage ../development/python-modules/tensorflow {
     inherit (pkgs.darwin) cctools;
     cudaSupport = pkgs.config.cudaSupport or false;
-    cudatoolkit = pkgs.cudatoolkit_11_0;
-    cudnn = pkgs.cudnn_cudatoolkit_11_0;
+    cudatoolkit = pkgs.cudatoolkit_11_2;
+    cudnn = pkgs.cudnn_cudatoolkit_11_2;
     nccl = pkgs.nccl_cudatoolkit_11;
     inherit (pkgs.darwin.apple_sdk.frameworks) Foundation Security;
     flatbuffers-core = pkgs.flatbuffers;