diff --git a/pkgs/development/python-modules/pwntools/default.nix b/pkgs/development/python-modules/pwntools/default.nix
index 6a20a5d4bf27..dad2c04b0d6f 100644
--- a/pkgs/development/python-modules/pwntools/default.nix
+++ b/pkgs/development/python-modules/pwntools/default.nix
@@ -1,4 +1,5 @@
 { lib
+, stdenv
 , buildPythonPackage
 , debugger
 , fetchPypi
@@ -77,7 +78,7 @@ buildPythonPackage rec {
     installShellCompletion --bash extra/bash_completion.d/shellcraft
   '';
 
-  postFixup = ''
+  postFixup = lib.optionalString (!stdenv.isDarwin) ''
     mkdir -p "$out/bin"
     makeWrapper "${debugger}/bin/${debuggerName}" "$out/bin/pwntools-gdb"
   '';
diff --git a/pkgs/development/python-modules/rpyc/default.nix b/pkgs/development/python-modules/rpyc/default.nix
index d9b81ddf5807..5d9c5958bd55 100644
--- a/pkgs/development/python-modules/rpyc/default.nix
+++ b/pkgs/development/python-modules/rpyc/default.nix
@@ -1,4 +1,5 @@
 { lib
+, stdenv
 , buildPythonPackage
 , fetchFromGitHub
 , hatchling
@@ -50,6 +51,8 @@ buildPythonPackage rec {
     "rpyc"
   ];
 
+  doCheck = !stdenv.isDarwin;
+
   meta = with lib; {
     description = "Remote Python Call (RPyC), a transparent and symmetric RPC library";
     homepage = "https://rpyc.readthedocs.org";