diff --git a/pkgs/applications/audio/famistudio/default.nix b/pkgs/applications/audio/famistudio/default.nix
index 81a2646ad74a..89d684523755 100644
--- a/pkgs/applications/audio/famistudio/default.nix
+++ b/pkgs/applications/audio/famistudio/default.nix
@@ -2,31 +2,35 @@
 , stdenv
 , fetchzip
 , autoPatchelfHook
+, dotnet-runtime
+, ffmpeg
+, libglvnd
 , makeWrapper
-, mono
 , openal
-, libGL
 }:
 
 stdenv.mkDerivation rec {
   pname = "famistudio";
-  version = "4.0.6";
+  version = "4.1.1";
 
   src = fetchzip {
     url = "https://github.com/BleuBleu/FamiStudio/releases/download/${version}/FamiStudio${lib.strings.concatStrings (lib.splitVersion version)}-LinuxAMD64.zip";
     stripRoot = false;
-    sha256 = "sha256-Se9EIQTjZQM5qqzlEB4hGVRHDFdu6GecNGpw9gYMbW4=";
+    hash = "sha256-fRNjboCfymBhr7Eg5ENnO1fchX0oTdeaJJ0SC3BKTVI=";
   };
 
+  strictDeps = true;
+
   nativeBuildInputs = [
     autoPatchelfHook
     makeWrapper
   ];
 
   buildInputs = [
-    mono
+    dotnet-runtime
+    ffmpeg
+    libglvnd
     openal
-    libGL
   ];
 
   dontConfigure = true;
@@ -38,9 +42,10 @@ stdenv.mkDerivation rec {
     mkdir -p $out/{bin,lib/famistudio}
     mv * $out/lib/famistudio
 
-    makeWrapper ${mono}/bin/mono $out/bin/famistudio \
-      --add-flags $out/lib/famistudio/FamiStudio.exe \
-      --prefix LD_LIBRARY_PATH : ${lib.makeLibraryPath [ libGL ]}
+    makeWrapper ${lib.getExe dotnet-runtime} $out/bin/famistudio \
+      --add-flags $out/lib/famistudio/FamiStudio.dll \
+      --prefix LD_LIBRARY_PATH : ${lib.makeLibraryPath [ libglvnd ]} \
+      --prefix PATH : ${lib.makeBinPath [ ffmpeg ]}
 
     # Bundled openal lib freezes the application
     rm $out/lib/famistudio/libopenal32.so