diff --git a/pkgs/development/python-modules/sigrok/default.nix b/pkgs/development/python-modules/sigrok/default.nix
new file mode 100644
index 000000000000..b8b925ba6b16
--- /dev/null
+++ b/pkgs/development/python-modules/sigrok/default.nix
@@ -0,0 +1,62 @@
+{ lib
+, stdenv
+, libsigrok
+, toPythonModule
+, python
+, autoreconfHook
+, pythonImportsCheckHook
+, pythonCatchConflictsHook
+, swig
+, setuptools
+, numpy
+, pygobject3
+}:
+
+# build libsigrok plus its Python bindings. Unfortunately it does not appear
+# to be possible to build them separately, at least not easily.
+toPythonModule ((libsigrok.override {
+  inherit python;
+}).overrideAttrs (orig: {
+  pname = "${python.libPrefix}-sigrok";
+
+  patches = orig.patches or [] ++ [
+    # Makes libsigrok install the bindings into site-packages properly (like
+    # we expect) instead of making a version-specific *.egg subdirectory.
+    ./python-install.patch
+  ];
+
+  nativeBuildInputs = orig.nativeBuildInputs or [] ++ [
+    autoreconfHook
+    setuptools
+    swig
+    numpy
+  ] ++ lib.optionals (stdenv.hostPlatform == stdenv.buildPlatform) [
+    pythonImportsCheckHook
+    pythonCatchConflictsHook
+  ];
+
+  buildInputs = orig.buildInputs or [] ++ [
+    pygobject3 # makes headers available the configure script checks for
+  ];
+
+  propagatedBuildInputs = orig.propagatedBuildInputs or [] ++ [
+    pygobject3
+    numpy
+  ];
+
+  postInstall = ''
+    ${orig.postInstall or ""}
+
+    # for pythonImportsCheck
+    export PYTHONPATH="$out/${python.sitePackages}:$PYTHONPATH"
+  '';
+
+  pythonImportsCheck = [ "sigrok" "sigrok.core" ];
+
+  meta = orig.meta // {
+    description = "Python bindings for libsigrok";
+    maintainers = orig.meta.maintainers ++ [
+      lib.maintainers.sternenseemann
+    ];
+  };
+}))
diff --git a/pkgs/development/python-modules/sigrok/python-install.patch b/pkgs/development/python-modules/sigrok/python-install.patch
new file mode 100644
index 000000000000..9c25eab6f39a
--- /dev/null
+++ b/pkgs/development/python-modules/sigrok/python-install.patch
@@ -0,0 +1,16 @@
+diff --git a/Makefile.am b/Makefile.am
+index 280cf64d..e10eb79f 100644
+--- a/Makefile.am
++++ b/Makefile.am
+@@ -888,8 +888,9 @@ $(PDIR)/timestamp: $(PDIR)/sigrok/core/classes.i \
+ 
+ python-install:
+ 	$(AM_V_at)$(MKDIR_P) "$(DESTDIR)$(prefix)" "$(DESTDIR)$(exec_prefix)"
+-	destdir='$(DESTDIR)'; $(setup_py) install $${destdir:+"--root=$$destdir"} \
+-		--prefix "$(prefix)" --exec-prefix "$(exec_prefix)"
++	destdir='$(DESTDIR)'; $(setup_py) install --root=$${destdir:-/} \
++		--prefix "$(prefix)" --exec-prefix "$(exec_prefix)" \
++		--single-version-externally-managed
+ 
+ python-clean:
+ 	-$(AM_V_at)rm -f $(PDIR)/timestamp
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 24a0dcb52fc3..0332a01ef6d1 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -8925,6 +8925,8 @@ in {
 
   signedjson = callPackage ../development/python-modules/signedjson { };
 
+  sigrok = callPackage ../development/python-modules/sigrok { };
+
   sigtools = callPackage ../development/python-modules/sigtools { };
 
   simanneal = callPackage ../development/python-modules/simanneal { };