diff --git a/pkgs/development/python-modules/lzstring/default.nix b/pkgs/development/python-modules/lzstring/default.nix
deleted file mode 100644
index 99ae373d063b..000000000000
--- a/pkgs/development/python-modules/lzstring/default.nix
+++ /dev/null
@@ -1,26 +0,0 @@
-{
-  lib,
-  buildPythonPackage,
-  fetchPypi,
-  future,
-}:
-
-buildPythonPackage rec {
-  pname = "lzstring";
-  version = "1.0.4";
-  format = "setuptools";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "18ly9pppy2yspxzw7k1b23wk77k7m44rz2g0271bqgqrk3jn3yhs";
-  };
-
-  propagatedBuildInputs = [ future ];
-
-  meta = {
-    description = "lz-string for python";
-    homepage = "https://github.com/gkovacs/lz-string-python";
-    license = lib.licenses.mit;
-    maintainers = with lib.maintainers; [ obadz ];
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 610a514024d7..eef36ba408a9 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -249,6 +249,7 @@ mapAliases {
   logilab_common = throw "'logilab_common' has been renamed to/replaced by 'logilab-common'"; # Converted to throw 2025-10-29
   loo-py = throw "'loo-py' has been renamed to/replaced by 'loopy'"; # Converted to throw 2025-10-29
   lxml-stubs = throw "'lxml-stubs' has been removed as it was broken and unmaintained upstream. Consider using 'types-lxml' instead."; # Converted to throw 2025-11-07
+  lzstring = throw "'lzstring' has been removed as it was unmaintained upstream"; # Added 2025-11-22
   mac_alias = throw "'mac_alias' has been renamed to/replaced by 'mac-alias'"; # Converted to throw 2025-10-29
   macropy = throw "macropy has been removed as it was broken since 2020"; # added 2025-10-04
   Mako = throw "'Mako' has been renamed to/replaced by 'mako'"; # Converted to throw 2025-10-29
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 0a4223d2d2eb..cf49f98f3e6a 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -9036,8 +9036,6 @@ self: super: with self; {
 
   lzfse = callPackage ../development/python-modules/lzfse { };
 
-  lzstring = callPackage ../development/python-modules/lzstring { };
-
   m2crypto = callPackage ../development/python-modules/m2crypto { };
 
   m2r = callPackage ../development/python-modules/m2r { };