diff --git a/pkgs/development/python-modules/uamqp/clang-fix-incompatible-function-pointer-conversion.patch b/pkgs/development/python-modules/uamqp/clang-fix-incompatible-function-pointer-conversion.patch
new file mode 100644
index 000000000000..ed177797da0c
--- /dev/null
+++ b/pkgs/development/python-modules/uamqp/clang-fix-incompatible-function-pointer-conversion.patch
@@ -0,0 +1,13 @@
+diff --git a/src/message_receiver.pyx b/src/message_receiver.pyx
+index b99647c..479cc9c 100644
+--- a/src/message_receiver.pyx
++++ b/src/message_receiver.pyx
+@@ -120,7 +120,7 @@ cdef class cMessageReceiver(StructBase):
+ 
+ #### Callbacks (context is a MessageReceiver instance)
+ 
+-cdef void on_message_receiver_state_changed(void* context, c_message_receiver.MESSAGE_RECEIVER_STATE_TAG new_state, c_message_receiver.MESSAGE_RECEIVER_STATE_TAG previous_state):
++cdef void on_message_receiver_state_changed(const void* context, c_message_receiver.MESSAGE_RECEIVER_STATE_TAG new_state, c_message_receiver.MESSAGE_RECEIVER_STATE_TAG previous_state):
+     if context != NULL:
+         context_pyobj = <PyObject*>context
+         if context_pyobj.ob_refcnt == 0: # context is being garbage collected, skip the callback
diff --git a/pkgs/development/python-modules/uamqp/default.nix b/pkgs/development/python-modules/uamqp/default.nix
index 207ad3d43727..c306068f7fdb 100644
--- a/pkgs/development/python-modules/uamqp/default.nix
+++ b/pkgs/development/python-modules/uamqp/default.nix
@@ -27,6 +27,9 @@ buildPythonPackage rec {
 
   patches = lib.optionals (stdenv.isDarwin && stdenv.isx86_64) [
     ./darwin-azure-c-shared-utility-corefoundation.patch
+  ] ++ [
+    # Fix incompatible function pointer conversion error with clang 16.
+    ./clang-fix-incompatible-function-pointer-conversion.patch
   ];
 
   postPatch = lib.optionalString (stdenv.isDarwin && !stdenv.isx86_64) ''