diff --git a/pkgs/development/python-modules/pylibjpeg/default.nix b/pkgs/development/python-modules/pylibjpeg/default.nix
index 155b3f1fe8c0..2e253d8d63b3 100644
--- a/pkgs/development/python-modules/pylibjpeg/default.nix
+++ b/pkgs/development/python-modules/pylibjpeg/default.nix
@@ -9,6 +9,7 @@
   pydicom,
   pylibjpeg-data,
   pylibjpeg-libjpeg,
+  pylibjpeg-openjpeg,
 }:
 
 buildPythonPackage rec {
@@ -29,6 +30,12 @@ buildPythonPackage rec {
 
   dependencies = [ numpy ];
 
+  optional-dependencies = {
+    libjpeg = [ pylibjpeg-libjpeg ];
+    openjpeg = [ pylibjpeg-openjpeg ];
+    #rle = [ pylibjpeg-rle ]; # not in Nixpkgs
+  };
+
   nativeCheckInputs = [
     pytestCheckHook
     pydicom