diff --git a/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml b/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml
index a020a52cf7cd..507fc61f8bb3 100644
--- a/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml
+++ b/nixos/doc/manual/from_md/release-notes/rl-2205.section.xml
@@ -215,6 +215,12 @@
           <literal>virtualisation.docker.daemon.settings</literal>.
         </para>
       </listitem>
+      <listitem>
+        <para>
+          opensmtpd-extras is no longer build with python2 scripting
+          support due to python2 deprecation in nixpkgs
+        </para>
+      </listitem>
       <listitem>
         <para>
           The <literal>autorestic</literal> package has been upgraded
diff --git a/nixos/doc/manual/release-notes/rl-2205.section.md b/nixos/doc/manual/release-notes/rl-2205.section.md
index 768766ad249f..490afc0954fd 100644
--- a/nixos/doc/manual/release-notes/rl-2205.section.md
+++ b/nixos/doc/manual/release-notes/rl-2205.section.md
@@ -72,6 +72,8 @@ In addition to numerous new and upgraded packages, this release has the followin
 
 - If you previously used `/etc/docker/daemon.json`, you need to incorporate the changes into the new option `virtualisation.docker.daemon.settings`.
 
+- opensmtpd-extras is no longer build with python2 scripting support due to python2 deprecation in nixpkgs
+
 - The `autorestic` package has been upgraded from 1.3.0 to 1.5.0 which introduces breaking changes in config file, check [their migration guide](https://autorestic.vercel.app/migration/1.4_1.5) for more details.
 
 - For `pkgs.python3.pkgs.ipython`, its direct dependency `pkgs.python3.pkgs.matplotlib-inline`
diff --git a/pkgs/servers/mail/opensmtpd/extras.nix b/pkgs/servers/mail/opensmtpd/extras.nix
index 65ff08b45396..5759e57d3b49 100644
--- a/pkgs/servers/mail/opensmtpd/extras.nix
+++ b/pkgs/servers/mail/opensmtpd/extras.nix
@@ -1,6 +1,5 @@
-{ lib, stdenv, fetchurl, openssl, libevent, libasr,
-  python2, pkg-config, lua5, perl, libmysqlclient, postgresql, sqlite, hiredis,
-  enablePython ? true,
+{ lib, stdenv, fetchurl, openssl, libevent, libasr, ncurses,
+  pkg-config, lua5, perl, libmysqlclient, postgresql, sqlite, hiredis,
   enableLua ? true,
   enablePerl ? true,
   enableMysql ? true,
@@ -20,7 +19,7 @@ stdenv.mkDerivation rec {
 
   nativeBuildInputs = [ pkg-config ];
   buildInputs = [ openssl libevent
-    libasr python2 lua5 perl libmysqlclient postgresql sqlite hiredis ];
+    libasr lua5 perl libmysqlclient postgresql sqlite hiredis ];
 
   configureFlags = [
     "--sysconfdir=/etc"
@@ -48,13 +47,6 @@ stdenv.mkDerivation rec {
     "--with-scheduler-ram"
     "--with-scheduler-stub"
 
-  ] ++ lib.optionals enablePython [
-    "--with-python=${python2}"
-    "--with-filter-python"
-    "--with-queue-python"
-    "--with-table-python"
-    "--with-scheduler-python"
-
   ] ++ lib.optionals enableLua [
     "--with-lua=${pkg-config}"
     "--with-filter-lua"