diff --git a/pkgs/development/python-modules/hdf5plugin/default.nix b/pkgs/development/python-modules/hdf5plugin/default.nix
index 2476d3bdc4db..e4731521e769 100644
--- a/pkgs/development/python-modules/hdf5plugin/default.nix
+++ b/pkgs/development/python-modules/hdf5plugin/default.nix
@@ -57,6 +57,16 @@ buildPythonPackage (finalAttrs: {
     zstd
   ];
 
+  # devendor
+  postPatch = ''
+    rm -rf lib/c-blosc
+    rm -rf lib/c-blosc2
+    rm -rf lib/bzip2
+    rm -rf lib/charls
+    rm -rf lib/zfp
+    rm -rf lib/zstd
+  '';
+
   # opt-in to use use system libs instead
   env.HDF5PLUGIN_SYSTEM_LIBRARIES = lib.concatStringsSep "," [
     "blosc"