diff --git a/pkgs/development/python-modules/gmpy2/default.nix b/pkgs/development/python-modules/gmpy2/default.nix
index 7bf82ed02b2d..58f4cc08f672 100644
--- a/pkgs/development/python-modules/gmpy2/default.nix
+++ b/pkgs/development/python-modules/gmpy2/default.nix
@@ -51,11 +51,17 @@ buildPythonPackage rec {
     mpmath
   ];
 
-  disabledTests = lib.optionals (stdenv.isLinux && stdenv.isAarch64) [
-    # issue with some overflow logic
-    "test_mpz_to_bytes"
-    "test_mpz_from_bytes"
-  ];
+  disabledTests =
+    lib.optionals (stdenv.isLinux && stdenv.isAarch64) [
+      # issue with some overflow logic
+      "test_mpz_to_bytes"
+      "test_mpz_from_bytes"
+    ]
+    ++ lib.optionals stdenv.isDarwin [
+      # TypeError: mpq() requires numeric or string argument
+      # not sure why it only fails on Darwin
+      "test_mpq_from_Decimal"
+    ];
 
   pythonImportsCheck = [ "gmpy2" ];